{"title":"儿童继发于着色性干皮病的斯皮兹黑色素瘤:1例报告","authors":"Zhen Gao, S.H. Chang","doi":"10.1097/IJ9.0000000000000088","DOIUrl":null,"url":null,"abstract":"A 6-year-old boy presented with a 5-year history of pigmentation on the face, neck, and hands. On examination, the patient had extreme photophobia. There was multiple freckles-like pigmentations on the face, neck, and back of both hands. Extremities were densely distributed. Multiple facial lesions, 1–2 cm2 in size, were also seen; most of them were ulcerated and had crusty patches. There was mild double eversion of the lower eyelids, with pigmentation and conjunctival redness in both eyes. Facial histopathologic findings: Spitz nevus-like malignant melanoma, Clark grade IV. A final diagnosis of melanoma secondary to xeroderma pigmentosa was made. According to the previous literature, the minimum age of patients with xeroderma pigmentosum combined with malignant melanoma is 8 years old, but the age, in this case, is 6 years old. In addition, extensive local excision of suspicious lesions early is of great significance for the prognosis of patients.","PeriodicalId":42930,"journal":{"name":"International Journal of Surgery-Oncology","volume":"38 1","pages":"e88 - e88"},"PeriodicalIF":0.3000,"publicationDate":"2020-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Spitz melanoma secondary to xeroderma pigmentosa in a child: a case report\",\"authors\":\"Zhen Gao, S.H. Chang\",\"doi\":\"10.1097/IJ9.0000000000000088\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A 6-year-old boy presented with a 5-year history of pigmentation on the face, neck, and hands. On examination, the patient had extreme photophobia. There was multiple freckles-like pigmentations on the face, neck, and back of both hands. Extremities were densely distributed. Multiple facial lesions, 1–2 cm2 in size, were also seen; most of them were ulcerated and had crusty patches. There was mild double eversion of the lower eyelids, with pigmentation and conjunctival redness in both eyes. Facial histopathologic findings: Spitz nevus-like malignant melanoma, Clark grade IV. A final diagnosis of melanoma secondary to xeroderma pigmentosa was made. According to the previous literature, the minimum age of patients with xeroderma pigmentosum combined with malignant melanoma is 8 years old, but the age, in this case, is 6 years old. In addition, extensive local excision of suspicious lesions early is of great significance for the prognosis of patients.\",\"PeriodicalId\":42930,\"journal\":{\"name\":\"International Journal of Surgery-Oncology\",\"volume\":\"38 1\",\"pages\":\"e88 - e88\"},\"PeriodicalIF\":0.3000,\"publicationDate\":\"2020-05-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Surgery-Oncology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1097/IJ9.0000000000000088\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Surgery-Oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/IJ9.0000000000000088","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ONCOLOGY","Score":null,"Total":0}
Spitz melanoma secondary to xeroderma pigmentosa in a child: a case report
A 6-year-old boy presented with a 5-year history of pigmentation on the face, neck, and hands. On examination, the patient had extreme photophobia. There was multiple freckles-like pigmentations on the face, neck, and back of both hands. Extremities were densely distributed. Multiple facial lesions, 1–2 cm2 in size, were also seen; most of them were ulcerated and had crusty patches. There was mild double eversion of the lower eyelids, with pigmentation and conjunctival redness in both eyes. Facial histopathologic findings: Spitz nevus-like malignant melanoma, Clark grade IV. A final diagnosis of melanoma secondary to xeroderma pigmentosa was made. According to the previous literature, the minimum age of patients with xeroderma pigmentosum combined with malignant melanoma is 8 years old, but the age, in this case, is 6 years old. In addition, extensive local excision of suspicious lesions early is of great significance for the prognosis of patients.