{"title":"6个月至12岁肺结核患儿血清锌水平","authors":"Parveen Mittal, Pancham Kalra","doi":"10.1016/j.pid.2015.06.002","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Tuberculosis is one of the most serious health problems in our country.</p><p>The association between tuberculosis and malnutrition is well recognized. Tuberculosis can lead to malnutrition, and malnutrition may predispose to tuberculosis. The micronutrient status in tuberculosis is affected significantly. Among the micronutrients, zinc plays a very important role as far as cell-mediated immunity is concerned. Limited data are available on the relationship between zinc levels and tuberculosis in childhood.</p></div><div><h3>Aim</h3><p>The present study was designed to estimate the serum zinc levels in children with tuberculosis and in children with malnutrition, and to compare the serum zinc levels between them.</p></div><div><h3>Methods</h3><p>Our study was conducted on 100 children in the age group of 6 months–12 years reporting to Department of Pediatrics, Rajindra Hospital, Patiala, out of which 50 children were those affected by tuberculosis and 50 children were those with malnutrition without tuberculosis. 50 age- and sex-matched children were taken as control.</p></div><div><h3>Results</h3><p>It was observed that the mean serum zinc levels in TB were 45.18<!--> <!-->±<!--> <!-->10.05<!--> <!-->μg/dl, in PEM were 53.04<!--> <!-->±<!--> <!-->7.13<!--> <!-->μg/dl while in controls they were 86.84<!--> <!-->±<!--> <!-->15.92<!--> <!-->μg/dl. It was seen that serum zinc levels were significantly low in children with TB as compared to controls (<em>p</em> <!--><<!--> <!-->0.0001). Serum zinc levels were found to be significantly low in children with PEM (but without TB) as compared to controls (<em>p</em> <!--><<!--> <!-->0.0001). Also, serum zinc levels were significantly low in children with TB when compared to children with PEM (without TB) (<em>p</em> <!--><<!--> <!-->0.05).</p></div><div><h3>Conclusion</h3><p>Serum zinc levels are significantly affected in tuberculosis.</p></div>","PeriodicalId":19984,"journal":{"name":"Pediatric Infectious Disease","volume":"7 2","pages":"Pages 36-40"},"PeriodicalIF":0.0000,"publicationDate":"2015-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.pid.2015.06.002","citationCount":"1","resultStr":"{\"title\":\"Serum zinc levels in children 6 months–12 years having tuberculosis\",\"authors\":\"Parveen Mittal, Pancham Kalra\",\"doi\":\"10.1016/j.pid.2015.06.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>Tuberculosis is one of the most serious health problems in our country.</p><p>The association between tuberculosis and malnutrition is well recognized. Tuberculosis can lead to malnutrition, and malnutrition may predispose to tuberculosis. The micronutrient status in tuberculosis is affected significantly. Among the micronutrients, zinc plays a very important role as far as cell-mediated immunity is concerned. Limited data are available on the relationship between zinc levels and tuberculosis in childhood.</p></div><div><h3>Aim</h3><p>The present study was designed to estimate the serum zinc levels in children with tuberculosis and in children with malnutrition, and to compare the serum zinc levels between them.</p></div><div><h3>Methods</h3><p>Our study was conducted on 100 children in the age group of 6 months–12 years reporting to Department of Pediatrics, Rajindra Hospital, Patiala, out of which 50 children were those affected by tuberculosis and 50 children were those with malnutrition without tuberculosis. 50 age- and sex-matched children were taken as control.</p></div><div><h3>Results</h3><p>It was observed that the mean serum zinc levels in TB were 45.18<!--> <!-->±<!--> <!-->10.05<!--> <!-->μg/dl, in PEM were 53.04<!--> <!-->±<!--> <!-->7.13<!--> <!-->μg/dl while in controls they were 86.84<!--> <!-->±<!--> <!-->15.92<!--> <!-->μg/dl. It was seen that serum zinc levels were significantly low in children with TB as compared to controls (<em>p</em> <!--><<!--> <!-->0.0001). Serum zinc levels were found to be significantly low in children with PEM (but without TB) as compared to controls (<em>p</em> <!--><<!--> <!-->0.0001). Also, serum zinc levels were significantly low in children with TB when compared to children with PEM (without TB) (<em>p</em> <!--><<!--> <!-->0.05).</p></div><div><h3>Conclusion</h3><p>Serum zinc levels are significantly affected in tuberculosis.</p></div>\",\"PeriodicalId\":19984,\"journal\":{\"name\":\"Pediatric Infectious Disease\",\"volume\":\"7 2\",\"pages\":\"Pages 36-40\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.pid.2015.06.002\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pediatric Infectious Disease\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2212832815000351\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pediatric Infectious Disease","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212832815000351","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Serum zinc levels in children 6 months–12 years having tuberculosis
Background
Tuberculosis is one of the most serious health problems in our country.
The association between tuberculosis and malnutrition is well recognized. Tuberculosis can lead to malnutrition, and malnutrition may predispose to tuberculosis. The micronutrient status in tuberculosis is affected significantly. Among the micronutrients, zinc plays a very important role as far as cell-mediated immunity is concerned. Limited data are available on the relationship between zinc levels and tuberculosis in childhood.
Aim
The present study was designed to estimate the serum zinc levels in children with tuberculosis and in children with malnutrition, and to compare the serum zinc levels between them.
Methods
Our study was conducted on 100 children in the age group of 6 months–12 years reporting to Department of Pediatrics, Rajindra Hospital, Patiala, out of which 50 children were those affected by tuberculosis and 50 children were those with malnutrition without tuberculosis. 50 age- and sex-matched children were taken as control.
Results
It was observed that the mean serum zinc levels in TB were 45.18 ± 10.05 μg/dl, in PEM were 53.04 ± 7.13 μg/dl while in controls they were 86.84 ± 15.92 μg/dl. It was seen that serum zinc levels were significantly low in children with TB as compared to controls (p < 0.0001). Serum zinc levels were found to be significantly low in children with PEM (but without TB) as compared to controls (p < 0.0001). Also, serum zinc levels were significantly low in children with TB when compared to children with PEM (without TB) (p < 0.05).
Conclusion
Serum zinc levels are significantly affected in tuberculosis.
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