Reeta Jaya Philip Sneha Mareen Varghese B S Premalatha, Anita Reddy
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The MTHFR gene predict weight change in drug-naive patients with bipolar II disorder
Objective: Patients with BP-II have a higher prevalence rate of metabolic disturbance and obesity than do the general population. Genetic variants of the methylene tetrahydrofolate reductase (MTHFR) gene have been regarded as predictors of weight gain in schizophrenia. In the present study, we investigated whether the MTHFR C677T polymorphism may predict changes in metabolic indices after 12 weeks of treatment in patients with BP-II.
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