[程序性血液透析患者动静脉瘘功能障碍重建的变异]。

B A Veselov, E P Burleva
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引用次数: 0

摘要

目的:本研究的目的是评估动静脉瘘原始重建在动脉和吻合口周围狭窄形成相关功能障碍发展中的疗效。患者和方法:本文介绍了两种原创性重建动静脉瘘的技术,用于狭窄血管改变导致血管通路功能障碍:侧对侧桡骨-头侧瘘的修复和gracz型动静脉瘘的修复。制定这些手术的主要概念是保留动静脉瘘功能部分的先前长度而不使其缩短。第1组11例,第2组19例。第一组和第二组患者血液透析替代治疗的平均持续时间分别为6.8年和5.6年。经临床检查,第一组患者超声造影术表现如下:吻合口近端桡动脉及前臂下三分之一局部狭窄(n=2),吻合口狭窄(n=3)或瘘静脉狭窄(n=6),距离吻合口1 ~ 5cm。所有组2患者均发现桡动脉沿前臂全长狭窄病变伴明显钙质沉积,包括合并吻合口周围狭窄(n=2)。结果:在第一组中,11例患者中有10例(91%)在1 - 4年的时间内获得了结果。其中2例患者死于“功能性”瘘管。其余患者继续接受程序性血液透析替代治疗。1例患者出现瘘静脉血栓,随后再通。重建血管通路的原发性和继发性(功能性)存活率分别为90%和100%。在第二组中,19名患者中有12名(63%)的结果是已知的(在相同的随访期间)。一名妇女死于心力衰竭,她的瘘管功能正常。另一名妇女被发现有一个未成熟的瘘管,并接受了环形臂基底动静脉瘘管的创建。另一名患者在创建动静脉瘘后出现肢体静脉功能不全,经前臂头静脉血管内激光凝固消除。第二组通路的主要生存率为83.3%。结论:所提出的动静脉瘘吻合口周围狭窄重建方法被证明是最佳的,因为它们保留了(第一组)或增加了(第二组)瘘功能部分的长度。
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[Variants of reconstructions of arterio-venous fistulas disfunction in patients on programmatic hemodialysis].

Objective: The purpose of this study was to assess efficacy of original reconstructions of arteriovenous fistulas in the development of their dysfunctions related to formation of arterial and perianastomotic stenosis.

Patients and methods: Presented herein are two techniques of original reconstructions of arteriovenous fistulas for stenotic vascular changes leading to dysfunction of a vascular access: modification of side-to-side radial-cephalic fistulas and modification of Gracz-type arteriovenous fistulas. The main concept while working out these operations was to preserve the previous length of the functioning portion of an arteriovenous fistula without its shortening. The first technique (Group One) was used in 11 patients and the second technique (Group Two) in 19 patients. The duration of replacement therapy with hemodialysis averagely amounted to 6.8 years and 5.6 years for Group Oneand Group Two patients, respectively. After clinical examination the findings of ultrasonographic mapping in Group One patients revealed the following alterations: local stenosis of the radial artery and lower third of the forearm proximal to the anastomosis (n=2), anastomotic stenosis (n=3) or fistula vein stenoses (n=6) at a distance of 1 to 5 cm from the anastomosis. All Group Two patients were found to have a stenosing lesion of the radial artery along the whole length of the forearm with pronounced calcinosis, including in combination with perianastomotic stenosis (n=2).

Results: In Group One, the results were available for 10 (91%) of 11 patients within a period from 1 year to 4 years. Of these, 2 patients died with 'functioning' fistulas. The remaining patients continue receiving replacement therapy by programmed hemodialysis. One patient developed fistula vein thrombosis followed by recanalization. Primary and secondary (functional) survival of the reconstructed vascular access amounted to 90% and 100%, respectively. In Group Two, the results were known for 12 (63%) of 19 patients (over the same period of follow up). One woman died of cardiac failure, with her fistula functioning. Another woman was found to have an immature fistula and underwent creation of a loop brachiobasilic arteriovenous fistula. A further patient after creation of an arteriovenous fistula developed venous insufficiency of the limb, which was eliminated by endovasal laser coagulation of the cephalic vein on the forearm. Primary survival of the access in Group Two amounted to 83.3%.

Conclusion: The proposed variants of reconstructions for perianastomotic stenosis of arteriovenous fistula proved optimal, since they preserve (Group One) or increase (Group Two) the length of the functioning portion of the fistula.

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