SARS-CoV-2感染伴多发性肌炎1例报告

Muhammad Hassan, Fatima Mustafa, N. Khan, Taimoor Hassan, Mansoor Iqbal Chaudhry, M. Badshah
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引用次数: 0

摘要

SARS-CoV-2感染最普遍和最不受关注的症状是肌痛、肌肉无力和身体疼痛。只有少数研究报道了Covid-19感染患者的多发性肌炎。至少三分之一的Covid-19综合征患者CPK水平升高。CPK升高的原因可能是细胞因子风暴或肌肉病毒感染。我们报告了一例患者在SARS-CoV-2引起的急性病毒前体症状消退后出现肌炎特征的病例。我们的患者具有与多发性肌炎相关的SARS-CoV-2的放射学和活检证实的神经肌肉表现。最初感染消退后不久,近端肌肉无力开始,并在数周或数月内逐渐恶化,导致行动不便。在调查之后,患者被诊断为多发性肌炎,并开始适当的治疗,他显示出改善的迹象。
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SARS-CoV-2 infection with polymyositis- a case report
Among the most prevalent and least addressed symptoms of SARS-CoV-2 infection are myalgia, muscle weakness, and body aches. Only a few studies have reported polymyositis in patients with Covid-19 infection. At least one-third of patients with Covid-19 syndrome had elevated CPK levels. The cause of elevated CPK can be a cytokine storm or viral infection of the muscles. We present a case in which our patient developed features of myositis following the resolution of an acute viral prodrome caused by SARS-CoV-2. Our patient had both radiological and biopsy-proven neuromuscular manifestations of SARS-CoV-2 associated with polymyositis. Proximal muscle weakness began shortly after the resolution of the initial infection and progressed gradually over weeks or months, resulting in immobility. In the aftermath of investigations, the patient was diagnosed with polymyositis, appropriate treatment was started, and he showed signs of improvement.
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