2型糖尿病患者尿视黄醇结合蛋白和视黄醇结合蛋白4电泳分析的意义

K. Kanamori, M. Kameko, H. Kitamura, Junichi Nishimaki, K. Shiba, Kenji Sato
{"title":"2型糖尿病患者尿视黄醇结合蛋白和视黄醇结合蛋白4电泳分析的意义","authors":"K. Kanamori, M. Kameko, H. Kitamura, Junichi Nishimaki, K. Shiba, Kenji Sato","doi":"10.2198/JELECTROPH.53.7","DOIUrl":null,"url":null,"abstract":"We measured the urinary excretion of retinol-binding protein (RBP), β 2 -microglobulin ( β 2 -m), albumin, and N-acetyl- β -D-glucosaminidase as well as serum glucose, RBP, β 2 -m, hemoglobin A1c, and creatinine in type 2 diabetes mellitus 158 patients. In urinary RBP, there was a significant difference between the patients who had nephropathy and those without complications. In the cases with nephropathy, urinary RBP had a significantly high value, but no significant difference was observed in the case with retinopathy. There were no significant correlations between urinary RBP and serum RBP. The index of correlation was 0.351. According The main for all three had molecular urinary RBP4, kDa for cases retinopathy, a and an light-colored band seen at 55 kDa, the possibility of early detection of retinopathy by examining these bands.","PeriodicalId":15059,"journal":{"name":"Journal of capillary electrophoresis","volume":"18 1","pages":"7-12"},"PeriodicalIF":0.0000,"publicationDate":"2009-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The usefulness of electrophoretic analysis of urinary retinol-binding protein and retinol-binding protein 4 in type 2 diabetes mellitus patients\",\"authors\":\"K. Kanamori, M. Kameko, H. Kitamura, Junichi Nishimaki, K. Shiba, Kenji Sato\",\"doi\":\"10.2198/JELECTROPH.53.7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We measured the urinary excretion of retinol-binding protein (RBP), β 2 -microglobulin ( β 2 -m), albumin, and N-acetyl- β -D-glucosaminidase as well as serum glucose, RBP, β 2 -m, hemoglobin A1c, and creatinine in type 2 diabetes mellitus 158 patients. In urinary RBP, there was a significant difference between the patients who had nephropathy and those without complications. In the cases with nephropathy, urinary RBP had a significantly high value, but no significant difference was observed in the case with retinopathy. There were no significant correlations between urinary RBP and serum RBP. The index of correlation was 0.351. According The main for all three had molecular urinary RBP4, kDa for cases retinopathy, a and an light-colored band seen at 55 kDa, the possibility of early detection of retinopathy by examining these bands.\",\"PeriodicalId\":15059,\"journal\":{\"name\":\"Journal of capillary electrophoresis\",\"volume\":\"18 1\",\"pages\":\"7-12\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2009-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of capillary electrophoresis\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2198/JELECTROPH.53.7\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of capillary electrophoresis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2198/JELECTROPH.53.7","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

我们测量了158例2型糖尿病患者的尿中视黄醇结合蛋白(RBP)、β 2 -微球蛋白(β 2 -m)、白蛋白和n -乙酰- β - d -氨基葡萄糖酶的排泄,以及血清葡萄糖、RBP、β 2 -m、血红蛋白A1c和肌酐的排泄。在尿RBP方面,肾病患者与无并发症患者有显著差异。肾病组尿RBP值明显偏高,而视网膜病变组尿RBP值无明显差异。尿RBP与血清RBP无显著相关性。相关指数为0.351。根据这三种主要为分子尿RBP4, kDa为视网膜病变的病例,a和一个浅色带见55 kDa,通过检查这些带早期发现视网膜病变的可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
The usefulness of electrophoretic analysis of urinary retinol-binding protein and retinol-binding protein 4 in type 2 diabetes mellitus patients
We measured the urinary excretion of retinol-binding protein (RBP), β 2 -microglobulin ( β 2 -m), albumin, and N-acetyl- β -D-glucosaminidase as well as serum glucose, RBP, β 2 -m, hemoglobin A1c, and creatinine in type 2 diabetes mellitus 158 patients. In urinary RBP, there was a significant difference between the patients who had nephropathy and those without complications. In the cases with nephropathy, urinary RBP had a significantly high value, but no significant difference was observed in the case with retinopathy. There were no significant correlations between urinary RBP and serum RBP. The index of correlation was 0.351. According The main for all three had molecular urinary RBP4, kDa for cases retinopathy, a and an light-colored band seen at 55 kDa, the possibility of early detection of retinopathy by examining these bands.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Electrophoretic extraction of protein complexes after separation and detection by a combined method of non-denaturing two-dimensional electrophoresis and reversible staining Use of Escherichia coli expression system for analyzing kinase motifs Proteomic analysis of spheroids of rhabdomyosarcoma cells cultured with decellularized muscle extracts Drug screening and kinase activity profiling of a novel patient-derived cell line of clear cell ovarian carcinoma Proteogenomic approach to drug targets in osteosarcomas with different original sites
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1