[麻风病的预后]。

R. Cochrane
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引用次数: 3

摘要

我们经常听到关于治疗的最终前景的不同和矛盾的陈述,因此总结一下目前的立场可能是有价值的。麻风病的预后或最终结局必须从与许多其他疾病略有不同的角度来看待。该病在后期阶段造成的毁容,常常导致的畸形,以及社会对麻风病人的耻辱感,所有这些都使我们的目标不仅仅是根除这种疾病,这一点至关重要。如果“治疗”的结果是残废和身体畸形,病人的社会地位丝毫没有改变,在大多数情况下,他不能恢复正常生活。因此,所有治疗的目标都是使病人摆脱活动性疾病的所有迹象,以及由此带来的耻辱。常伴随麻风病的发作。已故的汉森博士在他的书《麻风病的临床和病理方面》中最生动地总结了当时麻风病患者的情况,他说:“麻风病患者通常在疾病结束之前死亡。但在麻风病的黄斑麻醉(神经)形式的治疗是非常不同的。我们偶尔会遇到一个精力充沛、身体健康的完整的人,但通常只是一个可怜的人的原型,手脚或多或少瘫痪和变形,眼睛无法闭上,角膜的一部分是不透明的,眼泪从脸颊上流下来,面部肌肉瘫痪,无法闭上嘴巴,所以唾液不断地从嘴里流下来。然而,如果在这种情况下,这可以被看作是一种好处,这样的例子可能会活得很长,活得很长。”……”在结节性麻风中,麻风产品中的杆菌分解成颗粒,最终消失,麻风产品仅留下疤痕,无法识别麻风。偶有广泛的麻醉,是神经反应的结果;在。麻药形式是这种疾病的常规终止方式。在这两种情况下,leploy都完全愈合了。”然而,今天,完全治愈麻风病人而不造成永久性畸形的机会要大得多。然而,这是不可靠的……
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[Prognosis in leprosy].
O NE so often hears varying and contradictory state­ ments with regard to the ultimate outlook in treatment, that it may be of value to sum up the present position. The prognosis or ultimate end of leprosy has to be viewed from a slightly different standpoint than is the case in many other diseases. The disfigurement that the disease produces in th e later stages, the deformities that so often result, and the social stigma attached to the leper, all make it of utmost importance that something more than a mere eradication of the disease should be the aim. If the " cure " results i n mutiliation and physical deformity, the position of the patient socially is in no way changed, and he cannot in most cases resume normal life. Therefore the obj ect of all treat­ ment is to render th e patient free from all signs of active disease, and of the stigma which so. often accompany the arrest of leprosy. The late Dr. Hansen summed up the situation for the leper ill his day most vividly in his book "C linical and Pathological Aspects of Leprosy " when he said : " Lepers usually die before the disease has run its course. But in the maculo-anresthetic (nerve) form the cure of leprosy is very different. We have occasionally a complete subject with vigour and good health, but usually only a miserable rudi­ ment of a human being, with more or less paralysed and deformed hands and feet with unclosable eyes, of which part of the cornea is opaque, and from which tears run down over th e cheeks, and with paralysed fa cial muscles unable to close the mouth, so that saliva constantly dribbles from it. Such cases, may, however live long, and reach great ages, if under such circumstances this can be looke� upon as any advantage." ... " In nodular leprosy, the bacilli in the leprous products break up into granules which finally disappt:: ar, and there remains of the leprous product only a scar in which nothing leprous can be recognised. Occa�ion­ ally a widespread anresthesia, th e result of nerve affections; and in the. maculo-anresthetic form this is the regular termination of the disease. In both cases the leplOsy is completely healed." Today , however, the chances of completely healing the leper without permanent deformity are .much greater. It is, however, unreliable …
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A culturable Mycobacterium isolated from leproma of a leprosy-transmitted armadillo. [Surgical treatment for functional limb disturbances in leprosy (I) (author's transl)]. [Effect of antibiotics on the capsular structure of M. lepraemurium (author's transl)]. [Multiplication of Mycobacterium lepraemurium in cell-free liquid medium. 10. Factors involved in the starting material of M. lepraemurium for the growth in vitro and in vivo (author's transl)]. [Attempts at growth of M. leprae in mice (author's transl)].
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