肾性糖尿1例

Türkiye Klinikleri Journal of Case Reports Pub Date : 2018-01-01 DOI:10.5336/CASEREP.2018-61441

K. Kaynar, C. Şehit, A. Coşar, Gül Cebecioğlu Hasançebi

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引用次数: 0

摘要

通过糖异生和通过小管葡萄糖重吸收防止尿糖丢失在肾小球中自由过滤的葡萄糖的重吸收几乎完全发生在近端小管中。这种葡萄糖重吸收主要(90%)由钠-葡萄糖共转运蛋白2型(SGLT-2)和葡萄糖转运蛋白2 (GLUT2)进行。因此，在肾功能正常的患者中，通常在血浆葡萄糖浓度超过180 mg/dL (10 mmol/L)时才会出现明显的糖尿

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A Case with Renal Glycosuria

thesizing glucose via gluconeogenesis and preventing urinary glucose loss via tubulary glucose reabsorption.1 Reabsorption of glucose which is freely filtered in the glomeruli almost completely occur in proximal tubules only. This glucose reabsorption is mostly (90%) carried out by sodium-glucose cotransporters type 2 (SGLT-2) and glucose transporters 2 (GLUT2). So in patients with normal kidney function, significant glycosuria does not generally occur until the plasma glucose concentration exceeds 180 mg/dL (10 mmol/L).2

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Türkiye Klinikleri Journal of Case Reports

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