德干麻(爪哇黄麻)浆液配方开发的功能特性

Sushma Chaudhary, Manjul Singh, M. Srivastava, A. Rawat
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摘要

德干大麻含有丰富的粘液,价值巨大。本研究利用傅里叶变换红外光谱技术对该植物的粘液及其官能团进行了研究,为药物制剂的制备和开发提供了依据。浆液质量为9.54% w/w,颜色偏白,无味,有特有气味。理化性质表明,胶浆具有足够的水分(9.34% w/w), ph值为中性,在热水中可溶,在有机溶剂中不溶,在冷水中膨胀形成凝胶。对黏液的FT-IR分析表明,黏液中存在一些具有科学意义的主要标记物,特别是基于植物聚合物的赋形剂和制药产品中的涂层材料。
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Functional properties for formulation development in mucilage of Deccan hemp (Java jute)
Deccan hemp is rich in mucilage and of immense value. This study was performed to examine mucilage of the plant and its functional group with the help of FT-IR Spectroscopy for preparation and development of pharmaceutical formulation. Mucilage was found to be 9.54% w/w which was off white in colour, tasteless and with a characteristic odour. Physicochemical characterization revealed that mucilage has enough moisture i.e. 9.34 % w/w and is of neutral pH. It was found to be soluble in hot water and insoluble in organic solvents while in cold water mucilage swelled to form a gel. FT-IR analysis of mucilage showed the presence of as major markers that scope to be of scientific relevance particularly plant polymer based excipient and coating material in pharmaceutical products.
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