{"title":"计算蛋白质组学中的新特征表示和机器学习方法","authors":"Lei Chen","doi":"10.2174/157016461805210924161719","DOIUrl":null,"url":null,"abstract":"In recent years, protein-related data have grown rapidly with the application of novel methods and techniques. Several online public databases have been set up, and investigators can easily retrieve various data reported in them. Traditional computational methods to deal with these data are becoming more and more inappropriate because they are in different forms. Thus, novel data-driven computational methods are increasingly needed. This thematic issue collects six excellent papers, out of which three papers reviewed newly proposed methods of essential problems in computational proteomics and three research articles proposed novel computational methods to deal with specific problems.","PeriodicalId":50601,"journal":{"name":"Current Proteomics","volume":"29 1","pages":""},"PeriodicalIF":0.5000,"publicationDate":"2021-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Novel Feature Representation and Machine Learning Methods in Computational Proteomics\",\"authors\":\"Lei Chen\",\"doi\":\"10.2174/157016461805210924161719\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In recent years, protein-related data have grown rapidly with the application of novel methods and techniques. Several online public databases have been set up, and investigators can easily retrieve various data reported in them. Traditional computational methods to deal with these data are becoming more and more inappropriate because they are in different forms. Thus, novel data-driven computational methods are increasingly needed. This thematic issue collects six excellent papers, out of which three papers reviewed newly proposed methods of essential problems in computational proteomics and three research articles proposed novel computational methods to deal with specific problems.\",\"PeriodicalId\":50601,\"journal\":{\"name\":\"Current Proteomics\",\"volume\":\"29 1\",\"pages\":\"\"},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2021-11-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Proteomics\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.2174/157016461805210924161719\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"BIOCHEMICAL RESEARCH METHODS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Proteomics","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.2174/157016461805210924161719","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
Novel Feature Representation and Machine Learning Methods in Computational Proteomics
In recent years, protein-related data have grown rapidly with the application of novel methods and techniques. Several online public databases have been set up, and investigators can easily retrieve various data reported in them. Traditional computational methods to deal with these data are becoming more and more inappropriate because they are in different forms. Thus, novel data-driven computational methods are increasingly needed. This thematic issue collects six excellent papers, out of which three papers reviewed newly proposed methods of essential problems in computational proteomics and three research articles proposed novel computational methods to deal with specific problems.
Current ProteomicsBIOCHEMICAL RESEARCH METHODS-BIOCHEMISTRY & MOLECULAR BIOLOGY
CiteScore
1.60
自引率
0.00%
发文量
25
审稿时长
>0 weeks
期刊介绍:
Research in the emerging field of proteomics is growing at an extremely rapid rate. The principal aim of Current Proteomics is to publish well-timed in-depth/mini review articles in this fast-expanding area on topics relevant and significant to the development of proteomics. Current Proteomics is an essential journal for everyone involved in proteomics and related fields in both academia and industry.
Current Proteomics publishes in-depth/mini review articles in all aspects of the fast-expanding field of proteomics. All areas of proteomics are covered together with the methodology, software, databases, technological advances and applications of proteomics, including functional proteomics. Diverse technologies covered include but are not limited to:
Protein separation and characterization techniques
2-D gel electrophoresis and image analysis
Techniques for protein expression profiling including mass spectrometry-based methods and algorithms for correlative database searching
Determination of co-translational and post- translational modification of proteins
Protein/peptide microarrays
Biomolecular interaction analysis
Analysis of protein complexes
Yeast two-hybrid projects
Protein-protein interaction (protein interactome) pathways and cell signaling networks
Systems biology
Proteome informatics (bioinformatics)
Knowledge integration and management tools
High-throughput protein structural studies (using mass spectrometry, nuclear magnetic resonance and X-ray crystallography)
High-throughput computational methods for protein 3-D structure as well as function determination
Robotics, nanotechnology, and microfluidics.