在南埃塞俄比亚Arba Minch医院接受常规产前护理的孕妇中乙型肝炎病毒感染的血清阳性率和预测因素

T. Yohanes, Z. Zerdo, Nega Chufamo
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引用次数: 62

摘要

乙型肝炎病毒(HBV)是影响全世界数百万人的肝脏疾病的严重原因。当乙型肝炎病毒在怀孕期间获得,产前传播可能发生给胎儿。因此,本研究旨在估计在埃塞俄比亚南部Arba Minch医院产前诊所(ANC)就诊的孕妇中HBV感染的血清阳性率和相关因素。对2015年2月至4月在ANC就诊的232名孕妇进行了基于设施的横断面研究。采用问卷调查法收集社会人口学及相关因素数据。采用酶联免疫吸附法检测血清乙型肝炎表面抗原(HBsAg)。数据分析采用SPSS version 20。HBV感染的总体血清患病率为4.3% (95% CI: 2.2-6.9%)。多因素分析显示流产史(AOR = 7.775;95% CI: 1.538-39.301)和多个性伴侣(AOR = 7.189;95% CI: 1.039-49.755)是HBsAg血清阳性的独立预测因子。总之,HBV感染的流行率为中等水平。因此,筛查HBV感染应作为ANC的常规部分;应向从事堕胎工作的保健机构提供关于育龄妇女只有单一性伴侣以及在堕胎过程中采用无菌技术的健康信息。
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Seroprevalence and Predictors of Hepatitis B Virus Infection among Pregnant Women Attending Routine Antenatal Care in Arba Minch Hospital, South Ethiopia
Hepatitis B virus (HBV) is a serious cause of liver disease affecting millions of people throughout the world. When HBV is acquired during pregnancy, prenatal transmission can occur to the fetus. Therefore, this study is aimed at estimating seroprevalence and associated factors of HBV infection among pregnant women attending Antenatal Clinic (ANC) of Arba Minch Hospital, Southern Ethiopia. A facility based cross-sectional study was conducted on 232 pregnant women visiting ANC from February to April, 2015. Data regarding sociodemographic and associated factors were gathered using questionnaire. Serum samples were tested for hepatitis B surface antigen (HBsAg) by Enzyme Linked Immunosorbent Assay. Data was analyzed using SPSS version 20. The overall seroprevalence of HBV infection was 4.3% (95% CI: 2.2–6.9%). Multivariate analysis showed that history of abortion (AOR = 7.775; 95% CI: 1.538–39.301) and having multiple sexual partners (AOR = 7.189; 95% CI: 1.039–49.755) were independent predictors of HBsAg seropositivity. In conclusion, the prevalence of HBV infection is intermediate. Therefore, screening HBV infection should be routine part of ANC; health information on having single sexual partner for women of childbearing age and on following aseptic techniques during abortion should be provided to health facilities working on abortion.
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