COVID-19 mRNA疫苗诱导的淋巴结病在氟脱氧葡萄糖PET/CT扫描上模拟肺癌转移

Y. Hama, E. Tate
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引用次数: 0

摘要

一名66岁的IIA期非小细胞肺癌患者,4.5年前对放射治疗有完全反应,由于CA19-9水平升高,他接受了氟脱氧葡萄糖(FDG)正电子发射断层扫描/计算机断层扫描(PET/CT)。PET/CT扫描显示新的左腋窝和锁骨上淋巴结病变,FDG摄取增加,提示淋巴结转移。随后发现患者在PET/CT检查前7天接种了第二剂冠状病毒病2019 mRNA疫苗。回顾性评估显示左三角肌有模糊的线性代谢活动,注射部位有轻度FDG摄取。根据详细的病史和PET/CT表现,诊断为疫苗诱导的淋巴结病。随访6个月后确诊。
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COVID-19 mRNA vaccination-induced lymphadenopathy mimics lung cancer metastasis on fluorodeoxyglucose PET/CT scan
A 66-year-old man with stage IIA nonsmall cell lung cancer who had complete response to radiation therapy 4.5 years earlier underwent a fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) scan due to elevated CA19-9 levels. PET/CT scan showed a new cluster of left axillary and supraclavicular lymphadenopathy with increased FDG uptake suggesting lymph node metastasis. Later, it was found that the patient received the second dose of coronavirus disease 2019 mRNA vaccine 7 days before the PET/CT. Retrospective evaluation showed a vague linear-shaped metabolic activity in the left deltoid muscle with mild FDG uptake in the injection site. Based on the detailed history and PET/CT findings, a diagnosis of vaccination-induced lymphadenopathy was made. This diagnosis was confirmed after 6 months of follow-up.
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