尼拉吉蒿治疗潜力的研究进展

Bedadyuti Mohanty, S. Puri, V. Kesavan
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引用次数: 10

摘要

在现代治疗领域,药物严重缺乏新的治疗方法。一种新药要经过多年的研究和开发,才能进入市场,而且成本巨大。由于滥用药物而导致的日益严重的耐药性,已经使一些抗生素和其他救命药物失效。这两种趋势都意味着科学家和制药公司正在迫切地寻找新的药物来源,并且越来越多地将目光转向传统药物。非洲和亚洲国家的主要人口(80%)依靠传统草药治疗满足其初级卫生保健需求。当传统医学在其传统文化之外被采用时,它通常被称为替代医学。nilagirica在当地被称为“印度艾草”,属于菊科,被认为可以对抗许多疾病,因为它具有高含量的生物活性分子和精油。几个世纪以来,这种植物一直被用于抗菌、抗真菌、抗菌、抗丝虫病、杀虫、抗溃疡、抗癌、抗氧化和抗哮喘活性。本文对其体外培养、植物化学成分及治疗潜力等方面的研究进展进行了综述。本综述报道的药理学研究证实了nilagirica的治疗价值。该植物中广泛的化学成分的存在表明,在未来的几年里,该植物可以作为开发新型药物的有力材料,对各种疾病有良好的疗效。
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A Review on Therapeutic Potential of Artemisia nilagirica
In the modern world of therapy, medicines are in major short of new treatments. It can take many years for a new drug to get through the research and development pipeline to be available in the market and the cost is enormous. And the growing drug resistance caused by the misuse of medications, has rendered several antibiotics and other life-saving drugs useless. Both these trends mean that scientists and pharmaceutical companies are urgently looking for new drug sources and are increasingly turning their eyes to traditional medicine. Major population (80%) in countries of Africa and Asia depends on traditional herbal treatments for their primary health care needs. When adopted outside of its traditional culture, traditional medicine is often called alternative medicine. Artemisia nilagirica which is locally known as ‘Indian wormwood’ belongs to the Asteraceae family and is considered against many ailments as it is possessed to have high content of biologically active molecules and essential oils. The plant has been used since centuries in antimicrobial, antifungal, antibacterial, antifilarial, insecticidal, antiulcer, anticancer, antioxidant and anti-asthmatic activity. This review indicates the collected information on the description of in vitro cultivation, phytochemical constituents and therapeutic potential of A. nilagirica. The pharmacological studies reported in the present review confirms the therapeutic value of A. nilagirica. Presences of wide range of chemical compounds indicate that the plant could serve as a potent material for the development of novel agents having good efficacy in various disorders in the coming years.
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