急性髓性白血病治疗中罕见的中性粒细胞性汗腺炎一例报告

Nusrat Sanober, S. Talal, S. Ulahannan, J. Holter, A. Asch, M. Malla, Shannie Frisbie, S. Boddupalli
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引用次数: 1

摘要

我们报告一个罕见的62岁男性病例,他被诊断为急性髓性白血病,并在接受伊达柔比星和阿糖胞苷诱导化疗后,发展为双侧眼周皮肤皮肤病,涉及中性粒细胞外分泌汗腺炎。在诱导治疗的第7天,患者右眼周围出现肿胀和不适,并迅速发展到左眼。患者在局部类固醇和抗炎药物的支持下得到改善。中性粒细胞分泌性汗腺炎是一种典型的自限性疾病。在这种情况下,它似乎与潜在恶性肿瘤的预后较差无关。本报告的目的是阐明对中性粒细胞减少患者皮肤病变进行广泛鉴别的重要性,以及避免不适当的治疗以防止随后的不良事件。
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A Rare Presentation of Neutrophilic Eccrine Hidradenitis in the Management of Acute Myeloid Leukaemia: A Case Report
We present an unusual case of a 62-year-old male who was diagnosed with acute myeloid leukaemia and developed bilateral periocular skin dermatosis, concerning for neutrophilic eccrine hidradenitis, after receiving induction chemotherapy with Idarubicin and Cytarabine. On day seven of induction therapy, the patient developed swelling and discomfort around his right eye, which quickly progressed to involve the left side. Patient improved with supportive care with topical steroids and anti-inflammatory medications. Neutrophilic eccrine hidradenitis is typically a self-limited process. It does not appear to be associated with a worse prognosis for the underlying malignancy when occurring in that setting. The purpose of this report is to bring to light the importance of having a broad differential for dermal lesions in neutropenic patients and the avoidance of inappropriate therapy to prevent subsequent adverse events.
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