{"title":"调节微生物群预防腺瘤结肠癌的治疗方法和挑战","authors":"A. Patil, Neha Singh, Nita Pawar","doi":"10.53388/2023623016","DOIUrl":null,"url":null,"abstract":"New research suggests that gut microbiota helps adenoma colon cancer spread worldwide. This study seeks therapeutic microbiota changes to prevent adenoma colon cancer and discusses their drawbacks. Prebiotics feed good bacteria and promote the formation of short-chain fatty acids, which have anti-inflammatory and anti-cancer properties. To promote healthy gut bacteria and reduce adenoma risk, fiber-rich diets and particular dietary interventions are being researched. FMT (fecal microbiota transplantation) may help restore gut flora and prevent adenoma colon cancer, according to the study. FMT transfers healthy donor feces to patients to restore microbial diversity. Different gut flora, persons, and therapies make it tricky to draw conclusions. Personalizing therapeutic approaches to each person’s microbiota, host features, and genetic factors can improve treatment. Changing microorganisms may prevent adenoma colon cancer. Probiotics, prebiotics, dietary modifications, FMT, and bacteria metabolites may assist. More research is needed to determine the best ways to aid, solve difficulties, and personalize methods. We can prevent adenoma colon cancer and improve public health by learning more about gut flora and optimizing treatment methods.","PeriodicalId":50875,"journal":{"name":"Advances in Cancer Research","volume":"27 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Therapeutic approaches and challenges for modulating the microbiota to prevent adenoma colon cancer\",\"authors\":\"A. Patil, Neha Singh, Nita Pawar\",\"doi\":\"10.53388/2023623016\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"New research suggests that gut microbiota helps adenoma colon cancer spread worldwide. This study seeks therapeutic microbiota changes to prevent adenoma colon cancer and discusses their drawbacks. Prebiotics feed good bacteria and promote the formation of short-chain fatty acids, which have anti-inflammatory and anti-cancer properties. To promote healthy gut bacteria and reduce adenoma risk, fiber-rich diets and particular dietary interventions are being researched. FMT (fecal microbiota transplantation) may help restore gut flora and prevent adenoma colon cancer, according to the study. FMT transfers healthy donor feces to patients to restore microbial diversity. Different gut flora, persons, and therapies make it tricky to draw conclusions. Personalizing therapeutic approaches to each person’s microbiota, host features, and genetic factors can improve treatment. Changing microorganisms may prevent adenoma colon cancer. Probiotics, prebiotics, dietary modifications, FMT, and bacteria metabolites may assist. More research is needed to determine the best ways to aid, solve difficulties, and personalize methods. We can prevent adenoma colon cancer and improve public health by learning more about gut flora and optimizing treatment methods.\",\"PeriodicalId\":50875,\"journal\":{\"name\":\"Advances in Cancer Research\",\"volume\":\"27 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advances in Cancer Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.53388/2023623016\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in Cancer Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.53388/2023623016","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Medicine","Score":null,"Total":0}
Therapeutic approaches and challenges for modulating the microbiota to prevent adenoma colon cancer
New research suggests that gut microbiota helps adenoma colon cancer spread worldwide. This study seeks therapeutic microbiota changes to prevent adenoma colon cancer and discusses their drawbacks. Prebiotics feed good bacteria and promote the formation of short-chain fatty acids, which have anti-inflammatory and anti-cancer properties. To promote healthy gut bacteria and reduce adenoma risk, fiber-rich diets and particular dietary interventions are being researched. FMT (fecal microbiota transplantation) may help restore gut flora and prevent adenoma colon cancer, according to the study. FMT transfers healthy donor feces to patients to restore microbial diversity. Different gut flora, persons, and therapies make it tricky to draw conclusions. Personalizing therapeutic approaches to each person’s microbiota, host features, and genetic factors can improve treatment. Changing microorganisms may prevent adenoma colon cancer. Probiotics, prebiotics, dietary modifications, FMT, and bacteria metabolites may assist. More research is needed to determine the best ways to aid, solve difficulties, and personalize methods. We can prevent adenoma colon cancer and improve public health by learning more about gut flora and optimizing treatment methods.
期刊介绍:
Advances in Cancer Research (ACR) has covered a remarkable period of discovery that encompasses the beginning of the revolution in biology.
Advances in Cancer Research (ACR) has covered a remarkable period of discovery that encompasses the beginning of the revolution in biology. The first ACR volume came out in the year that Watson and Crick reported on the central dogma of biology, the DNA double helix. In the first 100 volumes are found many contributions by some of those who helped shape the revolution and who made many of the remarkable discoveries in cancer research that have developed from it.