Ruswana Anwar, Agnes Wijaya, David Halim, K. Mantilidewi, Saskia Medinawati Soraya, T. Djuwantono, W. Permadi, B. Handono, S. Krisnadi, Jusuf Effendi, D. Nataprawira
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引用次数: 0
摘要
目的:本研究旨在通过测定血清促卵泡激素(FSH)和抗勒氏激素(AMH)水平,探讨腹腔镜膀胱切除术对卵巢储备的影响。材料与方法:本前瞻性分析研究测量了2016年6月至8月在Dr. Hasan Sadikin医院行腹腔镜膀胱切除术的子宫内膜异位瘤患者基础FSH和AMH的变化。在研究之前,所有患者都获得了知情的书面同意。术前和术后1个月检测血清FSH和AMH水平。结果:共纳入31例患者,按20-35岁(n=16)和36-42岁(n=15)两个年龄段分为两组。两组腹腔镜膀胱切除术后血清FSH水平升高,AMH水平降低(P<0.001)。结论:子宫内膜瘤卵巢储备减少患者腹腔镜膀胱切除术的特点是血清FSH升高,血清AMH降低。
Laparoscopic Cystectomy of Endometrioma Outcomes on Follicle Stimulating Hormone and Anti-Müllerian Hormone Levels as Predictors of the Ovarian Reserve
Objectives: This study aimed to examine the effect of a laparoscopic cystectomy on ovarian reserve assessed by measuring the levels of serum follicle stimulating hormone (FSH) and anti-Müllerian hormone (AMH). Materials and Methods: This prospective, analytical study measured the changes of basal FSH and AMH in endometrioma patients undergoing laparoscopic cystectomy in Dr. Hasan Sadikin Hospital from June to August 2016. An informed written consent was obtained from all patients prior to the study. Their FSH and AMH serum levels were examined one month before and after the surgery. Results: A total of 31 patients were included in the study and divided into two groups based on two age ranges of 20-35 years (n=16) and 36-42 years (n=15). It was found that the FSH serum levels increased whereas the AMH serum levels decreased in both groups after laparoscopic cystectomy (P<0.001). Conclusions: Laparoscopic cystectomy of patients with reduced endometrioma ovarian reserve was characterized by elevation of FSH serum levels and reduction of AMH serum levels.