被动微波辐射测量(MWR)用于诊断COVID-19肺部并发症。

IF 0.8 4区 医学 Q4 SUBSTANCE ABUSE Heroin Addiction and Related Clinical Problems Pub Date : 2020-09-30 DOI:10.1101/2020.09.29.20202598
B. Osmonov, L. Ovchinnikov, C. Galazis, Berik Emilov, Mustafa Karaibragimov, Meder Seitov, S. Vesnin, Chingiz Mustafin, T. Kasymbekov, I. Goryanin
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引用次数: 0

摘要

世界卫生组织(WHO)宣布新冠肺炎为全球大流行。很明显,由于获得诊断测试和设备的机会有限,该病毒的传播大多是致命的。传统的x线摄影和CT仍然是胸部器官初步检查的主要方法。目前,大多数诊断都集中在新冠肺炎的PCR、胸部x线/CT表现上。然而,由于感染控制问题,CT室净化效率低下,以及中低收入国家缺乏CT可用性,CT存在问题。被动微波辐射测量(MWR)是一种廉价、无放射性、便携的技术。它已经被用于癌症和其他疾病的诊断。我们已经测试了MWR是否可用于COVID-19肺部并发症的早期诊断。这是一项随机对照试验(195名受试者),旨在评估在吉尔吉斯斯坦医院使用MWR对COVID-19引起的肺炎患者和健康个体进行诊断的有效性。我们测量了皮肤(IR)和内部(MWR)温度,通过记录通过胸壁在两侧30个对称点的肺投影的被动电磁辐射。通过x线/CT扫描和医生最终诊断(pn+/pn-)诊断肺炎和肺损伤。采用PCR检测covid- 19 (covid+/covid-)。pn-/covid-组和pn+/covid+组的检测结果最佳,敏感性为92%,特异性为75%。总体而言,本研究表明,使用MWR对COVID-19疑似肺炎患者进行筛查诊断是一种方便、安全的方法。由于MWR价格低廉,它将减轻患者和国家的经济负担,特别是中低收入国家
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Passive Microwave Radiometry (MWR) for diagnostics of COVID-19 lung complications.
The World Health Organization (WHO) declared COVID-19 it as a global pandemic. It becomes clear that the virus is spreading mostly deadly due to limited access to diagnostics tests and equipment. Traditional radiography and CT remain the main methods of the initial examination of the chest organs. Now, most of the diagnostics has been focused on PCR, chest X-Ray/CT manifestations of COVID-19. However, there are problems with CT due to infection control issues, the inefficiencies introduced in CT room decontamination, and lack of CT availability in LMIC (Low Middle Income Countries). Passive microwave radiometry (MWR) is a cheap, non-radioactive and portable technology. It has already been used for diagnostics of cancer, and other diseases. We have tested if MWR could be used for early diagnostics of pulmonary COVID-19 complications. This was a randomized controlled trial (195 subjects) to evaluate the effectiveness of diagnostics using MWR in patients with pneumonia caused by COVID-19 while they are in hospitals of Kyrgyzstan, and healthy individuals. We have measured skin (IR) and internal (MWR) temperature by recording passive electromagnetic radiation through the chest wall in the projection of the lungs at 30 symmetrical points on both sides. Pneumonia and lung damage were diagnosed by X-RAY/CT scan and doctor final diagnosis (pn+/pn-). COVID-19 was determined by PCR test (covid+/covid-). The best results were obtained between pn-/covid- and pn+/covid+ groups with sensitivity 92% and specificity 75%. Overall, the study suggests that the use of MWR is a convenient and safe method for screening diagnostics in COVID-19 patients with suspected pneumonia. Since MWR is an inexpensive, it will ease the financial burden for both patients and the countries, especially in LMIC
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