4-{[(E) - 1h -吲哚-3h-甲基]氨基}- 1,5-二甲基-2-苯基-1,2-二氢-3h-吡唑-3 -1及其Al(Iii), In(Iii)和Tl(I)配合物的合成、表征和微生物初步研究

A. Ocheni, P. Ukoha, P. Onoja
{"title":"4-{[(E) - 1h -吲哚-3h-甲基]氨基}- 1,5-二甲基-2-苯基-1,2-二氢-3h-吡唑-3 -1及其Al(Iii), In(Iii)和Tl(I)配合物的合成、表征和微生物初步研究","authors":"A. Ocheni, P. Ukoha, P. Onoja","doi":"10.3968/8519","DOIUrl":null,"url":null,"abstract":"4-{[(E)–1H–indol–3H–ylmethylidene]amino}–1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol–3-one and its Al(III), In(III) and Tl(I) Complexes have been synthesized and characterized by physical methods and spectral studies. All the complexes were purified and their structures were elucidated using melting point, stoichiometry, molar conductivity, UV-visible, infrared, nuclear magnetic resonance and GCMS Spectral Studies The geometry around the metals were deduced based on the spectral information and were found to be five coordinate in all the complexes. The Schiff base ligand is coordinated to the metals through the participation of its imine nitrogen, indole-nitrogen and the oxygen of the antipyrine moiety. These complexes were also tested against different bacteria and fungi using Agar well diffusion method to determine their antimicrobial potency and they were found sensitive against Escherichia Coli, Pseudomonas aeruginosa, Basillus subtilis and Candida albicans but none was found active against Staphylococcus aureus.","PeriodicalId":7348,"journal":{"name":"Advances in Natural Science","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2016-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Synthesis, Characterization and Preliminary Microbial Studies of 4-{[(E)–1h–Indol–3h–Lmethylidene]Amino}–1,5-Dimethyl-2-Phenyl-1,2-Dihydro-3h-Pyrazol–3-One and Its Al(Iii), In(Iii) and Tl(I) Complexes\",\"authors\":\"A. Ocheni, P. Ukoha, P. Onoja\",\"doi\":\"10.3968/8519\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"4-{[(E)–1H–indol–3H–ylmethylidene]amino}–1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol–3-one and its Al(III), In(III) and Tl(I) Complexes have been synthesized and characterized by physical methods and spectral studies. All the complexes were purified and their structures were elucidated using melting point, stoichiometry, molar conductivity, UV-visible, infrared, nuclear magnetic resonance and GCMS Spectral Studies The geometry around the metals were deduced based on the spectral information and were found to be five coordinate in all the complexes. The Schiff base ligand is coordinated to the metals through the participation of its imine nitrogen, indole-nitrogen and the oxygen of the antipyrine moiety. These complexes were also tested against different bacteria and fungi using Agar well diffusion method to determine their antimicrobial potency and they were found sensitive against Escherichia Coli, Pseudomonas aeruginosa, Basillus subtilis and Candida albicans but none was found active against Staphylococcus aureus.\",\"PeriodicalId\":7348,\"journal\":{\"name\":\"Advances in Natural Science\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-05-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advances in Natural Science\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3968/8519\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in Natural Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3968/8519","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

摘要

合成了4-{[(E) - 1h -吲哚- 3h -基甲基]氨基}- 1,5-二甲基-2-苯基-1,2-二氢- 3h -吡唑-3 -酮及其Al(III), In(III)和Tl(I)配合物,并通过物理方法和光谱研究对其进行了表征。通过熔点、化学计量、摩尔电导率、紫外可见、红外、核磁共振和GCMS光谱等方法对配合物进行了纯化,并对其结构进行了分析。根据光谱信息推导出配合物金属周围的几何形状,发现所有配合物均为五坐标。希夫碱配体通过其亚胺氮、吲哚氮和安替吡啶部分的氧的参与与金属配合。用琼脂孔扩散法测定了这些复合物对不同细菌和真菌的抑菌活性,发现它们对大肠杆菌、铜绿假单胞菌、枯草Basillus和白色念珠菌敏感,但对金黄色葡萄球菌没有活性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Synthesis, Characterization and Preliminary Microbial Studies of 4-{[(E)–1h–Indol–3h–Lmethylidene]Amino}–1,5-Dimethyl-2-Phenyl-1,2-Dihydro-3h-Pyrazol–3-One and Its Al(Iii), In(Iii) and Tl(I) Complexes
4-{[(E)–1H–indol–3H–ylmethylidene]amino}–1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol–3-one and its Al(III), In(III) and Tl(I) Complexes have been synthesized and characterized by physical methods and spectral studies. All the complexes were purified and their structures were elucidated using melting point, stoichiometry, molar conductivity, UV-visible, infrared, nuclear magnetic resonance and GCMS Spectral Studies The geometry around the metals were deduced based on the spectral information and were found to be five coordinate in all the complexes. The Schiff base ligand is coordinated to the metals through the participation of its imine nitrogen, indole-nitrogen and the oxygen of the antipyrine moiety. These complexes were also tested against different bacteria and fungi using Agar well diffusion method to determine their antimicrobial potency and they were found sensitive against Escherichia Coli, Pseudomonas aeruginosa, Basillus subtilis and Candida albicans but none was found active against Staphylococcus aureus.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Proterozoic Charnockites at 1.6 & 1.0 Ga in the Eastern Ghats Belt, India, Mirror Secular Evolution of Continental Crust Application and Research of High Precision Data Acquisition for Laser Gyro Assessement of the Relationship Between Increase in Heigth of Cassava Growth Rate and Agro-Climatic Parameters in Ilorin Area of Kwara State, Nigeria Stability Analysis of Eggshells Subjected to External Pressure A Study on the Characteristics of Water Consumption by Transpiration of Four Garden Plants in Linzhi City, Tibet
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1