一些新的(吡唑和三唑)香豆素衍生物的表面和简单合成

H. A. Latif, M. Barsy, E. Elrady
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引用次数: 0

摘要

由乙基-2-氧-2-香豆素-3-羧酸酯(1)与水合肼在含有催化量哌替啶混合物的乙醇中反应制备的2-氧-2- h -香豆素-3-碳肼(2)是合成一系列功能化香豆素的良好的起始中间体。因此,以化合物(2)为关键,通过与选定的试剂反应,合成了一些新的(吡唑、三唑)-2 - h香豆素-2- 1衍生物。
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Facial and Simple Synthesis of Some New (Pyrazole and Triazole) Coumarin Derivatives
2-oxo-2H-coumarin-3-carbohydrazide (2) which prepared from the reaction of ethyl-2-oxo-2Hcoumarin-3-carboxylate (1) with hydrazine hydrate in ethanol containing a catalytic amount of piperidine mixture consider a good and available starting intermediate for synthesis of series of functionalized coumarins. So, compound (2) was utilized as a key for the synthesis of some new (pyrazole, triazole)-2Hcoumarin-2-one derivatives by the reaction with some selected reagents.
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