乳腺假性化脓性乳腺炎间变性大细胞淋巴瘤的细胞学研究

Sailuja Maharjan, B. Satyal, Reena Baidya, P. Neupane
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摘要

乳腺是结外淋巴瘤的少见部位,占所有结外淋巴瘤的2.2%。B细胞淋巴瘤比T细胞淋巴瘤更常见。最常见的亚型是弥漫性大B细胞淋巴瘤。乳腺淋巴瘤具有非特异性的临床和放射学特征,诊断非常困难。我们报告一例罕见的原发性T细胞淋巴瘤,患者为20岁女性。超声检查误诊为脓肿,细针吸细胞学检查误诊为化脓性乳腺炎。然而,切除活检提示淋巴瘤,免疫组织化学证实为ALK阳性,间变性大细胞淋巴瘤。尽管FNAC是乳腺病变诊断三位一体的一部分,但潜在的缺陷也不能忽视,必须与活检相关联。
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Anaplastic large cell lymphoma of breast masquerading suppurative mastitis on cytology
Breast is an uncommon site of extra nodal lymphoma accounting for 2.2% of all extra nodal lymphomas. B cell lymphomas are more common than T cell types. The most common subtype is Diffuse Large B Cell Lymphoma. Breast lymphoma is very challenging to diagnose as it has nonspecific clinical and radiological features. We report a rare case of primary T cell lymphoma in a 20-year-old female. It was misdiagnosed as abscess on ultrasound and as suppurative mastitis on fine needle aspiration cytology (FNAC). However, excisional biopsy was suggestive of lymphoma and immunohistochemistry confirmed it as ALK positive, anaplastic large cell lymphoma. Even though FNAC is a part of the diagnostic triad for breast lesions, potential pitfalls cannot be overlooked and must be correlated with biopsy.
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