关于T细胞,临床血液学家应该知道些什么?

S. Sharma
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引用次数: 3

摘要

T细胞的旅程从骨髓开始,通过抵抗感染或作为记忆T细胞驻留在次要淋巴器官中,最终到达外周组织。胸腺在将温顺的T细胞前体转化为战士的过程中起着最重要的作用。T细胞是健康和疾病中最重要的细胞之一。各种疾病起源于T细胞的定性或定量缺陷,导致各种遗传和获得性疾病。这篇简单而简短的综述主要是对T细胞的基本认识和临床血液学家的观点。
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What a Clinical Hematologist Should Know about T Cells?
T cell’s journey begins from the bone marrow and ends in the peripheral tissues by either fighting the infections or residing in the secondary lymphoid organs as memory T cell. Thymus plays most important role in transforming a docile T cell precursor into a warrior. T cell is one of the most important cells in health and disease. Various diseases originate from qualitative or quantitative defects in T cells leading to various inherited and acquired diseases. This simple and short review is focused on the basic understanding and clinical hematologist’s perspective of T cells.
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