红花乙醇提取物对红细胞形态变化的影响

IF 0.9 4区生物学 Q4 PLANT SCIENCES Botanica Serbica Pub Date : 2023-01-01 DOI:10.2298/botserb2301087m

M. Marin, S. Branković

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引用次数: 0

摘要

本研究考察了大黄叶乙醇提取物的抗氧化活性及其对红细胞体外膜稳定性的影响。乙醇提取物具有很强的抗氧化活性，EC50 = 0.055mg/ml。以100 μ g/ml、200 μ g/ml、300 μ g/ml浓度的96%乙醇提取物处理大鼠血液，进行形态学分析。结果显示，高提取物浓度孵育的红细胞形状有显著差异。在浓度为200 μ g/ml时，观察到相当大的形态学变化，其特征是气孔细胞的百分比最高，而在浓度为300 μ g/ml时，观察到棘细胞形成的百分比最高。本研究结果表明，蒙大拿乙醇提取物可能对红细胞的膜稳定性有保护作用。

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The effect of the Satureja montana ethanol extract on the morphological changes of erythrocytes

The present study investigated the antioxidant activity of ethanol extracts of the leaves of Satureja montana and their influence on the membrane stability of erythrocytes ex vivo. The ethanol extracts showed a very potent antioxidant activity of EC50 = 0.055mg/ml. Rat blood samples were treated with 96% ethanol extracts in different concentrations of 100 ?g/ml, 200 ?g/ml, and 300 ?g/ml, and morphological analyses were carried out. The results showed significant differences in the shape of the erythrocytes incubated with higher extract concentrations. Considerable morphological changes were observed at a concentration of 200 ?g/ml which was characterised by the highest percentage of stomatocytes, while the highest percentage of echinocyte formation was observed at a concentration of 300 ?g/ml. The results of this investigation indicated that the ethanol extracts of S. montana exhibited a possible protective effect on the membrane stability of erythrocytes.

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来源期刊

Botanica Serbica Agricultural and Biological Sciences-Plant Science

CiteScore

1.40

自引率

12.50%

发文量

审稿时长

34 weeks

期刊介绍： Botanica Serbica publishes original research papers on all aspects of plant, fungal and microbial biology research including the disciplines of microbiology, mycology, lichenology, bryology, flora, vegetation, biogeography, systematics, taxonomy, plant biotechnology, plant cell biology, plant ecology, environmental plant biology, forestry, genomics, horticulture, limnology, metabolomics, molecular biology, proteomics, virology, plant conservation and protection, and wildlife and ecosystem management.