乙烯利对雌性小鼠体外受精及氧化应激的影响

R. Bagheri, Shiva Khezri, G. Najafi
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引用次数: 1

摘要

方法:在本实验研究中,将动物分为5组;对照组(不给药),假组(每天口服血清生理),乙烯利1(每天口服192 mg/kg),乙烯利2(每天口服240 mg/kg),乙烯利3(每天口服480 mg/kg)。在28天的治疗期结束时,将卵巢从体内取出进行体外受精。测定血清中氧化应激标志物丙二醛(MDA)和总抗氧化能力(TAC)。受精参数,包括卵母细胞百分比,受精率和胚胎质量,也进行了检查。数据分析采用单因素方差分析和Tukey事后检验。
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Evaluation of Ethephon on in vitro Fertilization and Oxidative Stress in Female mice
Methods: In this experimental study, the animals were divided into 5 groups; control (received no substances), sham (daily received serum physiology orally), ethephon 1 (daily received 192 mg/kg orally), ethephon 2 (daily received 240 mg/kg orally), ethephon 3 (daily received 480 mg/kg orally). At the end of the 28-day treatment period, the ovaries were removed from their body for in vitro fertilization. Oxidative stress markers, including malondialdehyde (MDA) and total antioxidant capacity (TAC), were measured in serum samples. Fertility parameters, including oocyte percentage, fertilization percentage, and embryo quality, were also examined. Data were analyzed using oneway ANOVA and Tukey’s post hoc test.
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