3日龄先天性心脏病新生儿SARS-CoV-2感染轻度症状1例

Azin Etemadimanesh, A. Ghasemi, M. Khodabandeh, H. Eshaghi
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摘要

背景:SARS-CoV-2作为冠状病毒家族的一员,在2019年底引发了全球大流行,并引起了人们对免疫缺陷个体发病率和死亡率的担忧。到目前为止,已有多例小儿感染SARS-CoV-2的病例报告,其中一些婴幼儿易感感染,特别是有先天性合并症的婴幼儿。在本报告中,我们讨论了患有心血管合并症的婴儿的SARS-COV-2感染的临床过程、给予的治疗和结果。病例介绍:我们描述了一个新生儿产后72小时转诊到医院,诊断为肺闭锁合并室间隔缺损(PA-VSD),随后被发现感染了SARS-COV-2病毒。患者表现为呼吸急促、嗜睡,其父亲近期有发热和肌痛史。根据伊朗卫生部制定的新冠肺炎治疗方案,患者接受了静脉输液和抗生素治疗,住院5天后出院,无进一步并发症。出院后2周,鼻咽标本SARS-CoV-2 RT-PCR阴性,转至心脏外科手术治疗。结论:本病例症状轻微,无需过度供氧支持,表明与成人相比,儿科COVID-19患者预后更好,并发症更少,即使在幼儿期和存在严重心脏并发症时也是如此。
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Mild Symptoms of SARS-CoV-2 Infection in a 3-Days-Old Newborn with Congenital Heart Disease: A Case Report
Background: SARS-CoV-2 as a member of Coronavirus family, caused a global pandemic in late 2019 and raised concerns about its morbidity and mortality among immune-deficient individuals. Till now, several pediatric cases infected with SARS-CoV-2 have been reported, and some have noted susceptibility to infection in infants and young children, especially those with congenital comorbidities. In this report, we discuss the clinical course, administered treatments, and outcomes of SARS-COV-2 infection in an infant suffering from cardiovascular comorbidity. Case Presentation: We describe a newborn referred to hospital 72 hours postpartum, diagnosed with pulmonary atresia with ventricular septal defect (PA-VSD), and subsequently found to be infected with the SARS-COV-2 virus. The patient presented with tachypnea, lethargy, and a history of recent fever and myalgia in his father. He received intravenous fluid and antibiotic therapy based on an established protocol for COVID-19 treatment by Iran health ministry and was discharged after five days of hospitalization without further complications. Two weeks after discharge, he was referred to the cardiac surgery department for surgical treatment after obtaining a negative result for nasopharyngeal sample SARS-CoV-2 RT-PCR. Conclusions: Mild symptoms and no need for excessive oxygen supports in the current case demonstrate pediatrics patients with COVID-19 have a better prognosis and fewer complications compared with adults, even at early childhood and with the presence of serious cardiac complications.
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