谁决定不遵医嘱出院:一项临床研究

Yu-lian hsieh, Hui-Tzu Huang, Ching Chen
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摘要

主观:为了减少非必要的医疗保健支出,防止患者发生不良后果,我们在本研究中旨在了解精神障碍患者违背医嘱出院的患病率和特征。方法:回顾性分析2013年1月1日至2018年8月31日台湾基隆长工纪念医院急性精神科住院患者的病历。结果:1237例患者中有100例(8.1%)出院。与正常出院患者相比,AMA出院患者在年龄(p < 0.05)、首次入院(p < 0.001)、共病性物质使用障碍(p < 0.05)、既往自杀未遂(p < 0.01)、住院时间(p < 0.001)等方面差异均有统计学意义。采用正向逐步logistic回归模型寻找影响AMA出院的因素,结果发现自杀企图史患者的比值比(1.931 [1.265 ~ 2.949],B = 0.658, p < 0.01)和首次精神科住院患者的比值比(3.435 [2.253 ~ 5.237],B = 1.234, p < 0.001)显著预测AMA患者出院。结论:自杀未遂史和首次入住精神科病房是影响AMA患者出院的最重要因素。我们认为,对照前瞻性研究可以加强研究结果,并更好地描述对AMA出院患者的影响。
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Who determines to discharge against medical advice from an acute psychiatric hospitalization: A clinical study
Subjective: To reduce the nonessential healthcare expenditure and to prevent patients from adverse consequences, we intended in this study to find the prevalence and characteristics of patients with psychiatric disorder with against medical advice (AMA) discharge. Methods: We did a review of medical records for patients who hospitalized on the acute psychiatric ward at Keelung Chang Gung Memorial Hospital in Taiwan from January 1, 2013, to August 31, 2018. Results: We found that 100 patients (8.1%) were discharged AMA out of total 1,237 discharges. Compared to patients with regular discharges, those with AMA discharge were significantly different between the groups in age (p < 0.05), first time admission (p < 0.001), comorbid substance use disorders (p < 0.05), previous suicide attempts (p < 0.01), and length of hospital stay (p < 0.001). With forward stepwise logistic regression model to look for the most influential predictors for AMA discharge, we found that odds ratio (95% confidence interval) of those with suicidal attempt history (1.931 [1.265–2.949], B = 0.658, p < 0.01) and those with the first-time psychiatric admission (3.435 [2.253–5.237], B = 1.234, p < 0.001) significantly predicted those AMA patients. Conclusion: The history of suicide attempt and first-time psychiatric ward admission is the most important predictors for patients with AMA discharge. We suggest that controlled prospective studies can strengthen the study findings and better describe the impact on patients with AMA discharge.
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