[90岁老人膀胱癌的预后]。

Q4 Medicine Japanese Journal of Urology Pub Date : 2021-04-20 DOI:10.5980/jpnjurol.112.58
Soichi Matsumura, Takahiro Yoshida, T. Imanaka, K. Yamanaka, H. Kishikawa
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引用次数: 0

摘要

(目的)评估老年膀胱癌患者数量和比例的时间变化。我们还回顾性调查了≥90岁的膀胱癌患者的临床结果。(患者和方法)我们评估了2008年至2018年在我院临床诊断为膀胱癌并接受经尿道膀胱肿瘤切除术(turt - bt)的≥90岁患者的数量和比例的时间变化。我们还评估了≥90岁膀胱癌患者的临床病理因素、围手术期结局和临床结局。(结果)≥90岁的膀胱癌患者数量和比例随时间增加而增加。本院共有39例≥90岁的患者行turt - bt,其中22例诊断为原发性膀胱癌。中位年龄为91岁。turt - bt术后未见≥III级并发症。6例pT1患者中有2例接受了第二次turt - bt。7例pT1疾病或原位癌患者中有2例接受膀胱内BCG治疗。在研究期间观察到6例死亡,其中2例死于膀胱癌。在turt - bt术后1年和3年,22例患者的总生存率分别为80.4%和68.9%。(结论)老年膀胱癌患者的数量和比例随着时间的推移而增加。目前的治疗标准包括二次turt - bt和膀胱内卡介苗治疗高风险非肌肉浸润性膀胱癌,但在90岁以上人群中应用不足。
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[OUTCOMES OF BLADDER CANCER IN NONAGENARIANS].
(Objectives) We evaluated the chronological change in the number and proportion of elderly patients with bladder cancer. We also retrospectively investigated the clinical outcomes of bladder cancer in patients of ≥90 years of age. (Patients and methods) We evaluated the chronological change in the number and proportion of patients of ≥90 years of age who were clinically diagnosed with bladder cancer and who underwent transurethral resection of a bladder tumor (TUR-BT) at our hospital between 2008 and 2018. We also assessed the clinicopathological factors, perioperative outcomes, and clinical outcomes in bladder cancer patients of ≥90 years of age. (Results) The number and proportion of bladder cancer patients of ≥90 years of age increased with time. A total of 39 patients of ≥90 years of age underwent TUR-BT at our hospital, among whom 22 were diagnosed with primary bladder cancer. The median age was 91 years. No grade ≥III complications were observed after TUR-BT. Two out of 6 with pT1 disease underwent second TUR-BT. Two out of 7 with pT1 disease or carcinoma in situ received intravesical BCG therapy. Six deaths were observed during the study period, 2 of which were due to bladder cancer. At 1 and 3 years after TUR-BT, the overall survival rates of the 22 patients were 80.4% and 68.9%, respectively. (Conclusions) The number and proportion of elderly patients with bladder cancer increased with time. The current standard of care including second TUR-BT and intravesical BCG therapy for high-risk non-muscle invasive bladder cancer was underutilized in nonagenarians.
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Japanese Journal of Urology
Japanese Journal of Urology Medicine-Urology
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