{"title":"氰胺氢相关的严重皮肤反应模拟多形性红斑和史蒂文斯-约翰逊综合征/中毒性表皮坏死松解","authors":"A. Inamadar, A. Palit","doi":"10.1159/000084697","DOIUrl":null,"url":null,"abstract":"Fifteen grapevine workers developed skin reactions resembling erythema multiforme (EM) and Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) following exposure to Dormex, a plant growth regulator, the active ingredient of which is hydrogen cyanamide. Five patients needed hospitalization, and all recovered following treatment. Whether these were contact EM-like reactions due to hydrogen cyanamide or classical EM, SJS-TEN induced by this chemical remains elusive. An awareness regarding the safe use of agricultural chemicals is needed among the general population.","PeriodicalId":12086,"journal":{"name":"Exogenous Dermatology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2005-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":"{\"title\":\"Hydrogen-Cyanamide-Related Severe Cutaneous Reactions Simulating Erythema multiforme and Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis\",\"authors\":\"A. Inamadar, A. Palit\",\"doi\":\"10.1159/000084697\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Fifteen grapevine workers developed skin reactions resembling erythema multiforme (EM) and Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) following exposure to Dormex, a plant growth regulator, the active ingredient of which is hydrogen cyanamide. Five patients needed hospitalization, and all recovered following treatment. Whether these were contact EM-like reactions due to hydrogen cyanamide or classical EM, SJS-TEN induced by this chemical remains elusive. An awareness regarding the safe use of agricultural chemicals is needed among the general population.\",\"PeriodicalId\":12086,\"journal\":{\"name\":\"Exogenous Dermatology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2005-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Exogenous Dermatology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1159/000084697\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Exogenous Dermatology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000084697","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Hydrogen-Cyanamide-Related Severe Cutaneous Reactions Simulating Erythema multiforme and Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis
Fifteen grapevine workers developed skin reactions resembling erythema multiforme (EM) and Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) following exposure to Dormex, a plant growth regulator, the active ingredient of which is hydrogen cyanamide. Five patients needed hospitalization, and all recovered following treatment. Whether these were contact EM-like reactions due to hydrogen cyanamide or classical EM, SJS-TEN induced by this chemical remains elusive. An awareness regarding the safe use of agricultural chemicals is needed among the general population.