氰胺氢相关的严重皮肤反应模拟多形性红斑和史蒂文斯-约翰逊综合征/中毒性表皮坏死松解

A. Inamadar, A. Palit
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引用次数: 4

摘要

15名葡萄藤工人在接触植物生长调节剂Dormex(其有效成分为氰胺氢)后出现了类似多形性红斑(EM)和史蒂文斯-约翰逊综合征/中毒性表皮坏死松解症(SJS/TEN)的皮肤反应。5例需要住院治疗,经治疗后全部康复。无论这些是由氰酰胺氢引起的接触EM样反应还是由经典EM引起的SJS-TEN,这种化学物质引起的SJS-TEN仍然是难以捉摸的。一般民众需要有安全使用农用化学品的意识。
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Hydrogen-Cyanamide-Related Severe Cutaneous Reactions Simulating Erythema multiforme and Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis
Fifteen grapevine workers developed skin reactions resembling erythema multiforme (EM) and Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) following exposure to Dormex, a plant growth regulator, the active ingredient of which is hydrogen cyanamide. Five patients needed hospitalization, and all recovered following treatment. Whether these were contact EM-like reactions due to hydrogen cyanamide or classical EM, SJS-TEN induced by this chemical remains elusive. An awareness regarding the safe use of agricultural chemicals is needed among the general population.
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Acknowledgement to Referees for Exogenous Dermatology 2004 Contents Vol. 3, 2004 Author Index Vol. 3, 2004 Is There Evidence that Geraniol Causes Allergic Contact Dermatitis? Subject Index Vol. 3, 2004
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