孟加拉国COVID-19患者发现延迟Cox比例风险模型的应用

Sujan Rudra, Shuva Das, Md. Ehsanul Hoque, A. Kalam, Mohammad Arifur Rahman
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引用次数: 4

摘要

目的:了解新冠肺炎(COVID-19)患者出现症状后近期进行诊断检查的生存率。目的是确定与延迟发现COVID-19患者相关的社会人口风险因素。方法:本横断面研究选择孟加拉国吉大港医学院分子生物学实验室诊断为COVID-19患者300例。数据收集于2020年5月至7月。通过电话访谈和实时逆转录聚合酶链式反应(rRT-PCR)的实验室诊断获得临床特征。应用Cox比例风险模型估计影响COVID-19患者检测延迟的危险因素。结果:女性死亡率比男性高44.9%,大学毕业生死亡率比本科生高32%,未婚者死亡率比已婚者高56%,不定期旅行和有症状患者接触者死亡率比非旅行者高86%。结论:COVID-19的早期诊断可以挽救大量生命,应特别重视显著的解释变量。
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Delay of Detection Of COVID-19 Patients In Bangladesh; An Application To Cox Proportional Hazard Model
Objective: To delineate the survival rate of the patients with coronavirus disease 2019 (COVID-19) who did the diagnostic tests lately after the development of symptoms. The aim is to determine the socio-demographic risk factors associated with the delay of the detection of COVID-19 patients. Methods: For this cross-sectional study, 300 patients were selected who were diagnosed as COVID-19 patients in the Molecular Biology Laboratory of Chittagong Medical College, Chattogram, Bangladesh. Data were collected from May to July 2020. Clinical characteristics were obtained from over phone interviews and laboratory diagnosis by Real-time Reverse Transcriptase Polymerase Chain Reaction (rRT-PCR). Cox proportional hazard model is applied to estimate risk factors affecting the delay of detection of COVID-19 patients.Result: Female mortality rate was 44.9% higher compared to males, graduates died 32% more than undergraduates, unmarried peoples’ death rate were 56% more than married and those who were in traveling irregularly and in contact with symptomatic patients, were 86% more died than non-travelers.Conclusion: Early diagnosis of COVID-19 can save a huge amount of lives and special attention should be emphasized on the significant explanatory variable.
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