维生素C,老化皮肤,皮肤健康

P. Humbert, L. Louvrier, P. Saas, C. Viennet
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引用次数: 3

摘要

维生素C是人体必需的营养素。维生素C以其抗氧化潜力而闻名。维生素C在生物体液中是一种有效的水溶性抗氧化剂。因此,局部服用维生素C不仅可以降低光老化的风险,还可以降低致癌的风险。除了抗氧化的特性,维生素C对胶原蛋白的合成也是必不可少的。维生素C刺激或恢复一些缺乏或紊乱的机制。局部应用维生素C可以部分恢复年轻皮肤表皮-真皮连接处的解剖结构。一项临床试验首次证实,与单独使用载体相比,局部应用5%维生素C超过6个月可显着改善光损伤皮肤的临床外观。在炎症性皮肤病中,即特应性皮炎和牛皮癣,进入真皮层的维生素C水平降低。此外,在贝特曼紫癜患者中进行的一项随机双盲比较研究表明,维生素C可能是主要的局部抗衰老药物之一。此外,紫外线照射后使用光防护防晒霜可以防止酸性抗坏血药真皮浓度的下降。事实上,摄入维生素C对皮肤有不同的好处,比如伤口愈合、皮肤老化和预防皮肤癌。
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Vitamin C, Aged Skin, Skin Health
Vitamin C is an essential nutriment for humans. Vitamin C is known for its antioxidant potential. Vitamin C acts as a potent water-soluble antioxidant in biological fluids. Thus, topical vitamin C will not only reduce the risks of development of photoaging but also could reduce the risk of carcinogenesis. In addition to its antioxidant properties, vitamin C is essential for collagen synthesis. Vitamin C stimulates or restores several mechanisms which are either deficient or disturbed. Topical application of vitamin C partially restores the anatomical structure of the epidermal-dermal junction in young skin. A clinical trial confirmed for the first time that topical application of 5% vitamin C over a period of 6 months significantly improves the clinical appearance of photodamaged skin when compared to the vehicle alone. In inflammatory skin diseases, that is, atopic dermatitis and psoriasis, vitamin C levels into the dermis are reduced. Moreover, a randomized double-blind comparative study conducted in patients with Bateman purpura showed a significant improvement that vitamin C is probably one of the main topical anti-aging agents. In addition, the use of photo-protective sunscreen after UV irradiation prevents the decrease of acid ascorbic dermis concentration. Indeed, the ingestion of vitamin C has different benefits on skin such as wound healing, cutaneous aging, and prevention of skin cancer.
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