需要机械通气的COVID-19患者早期气管切开与气管插管的比较

Mahdi Morshedi, Mohammad-Javad Babaei, Ali Bahramifar, E. Karimi, S. Najafizadeh-Sari, M. Raei, Hamed Gholizadeh
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引用次数: 0

摘要

背景:支持呼吸护理和气道管理在治疗新冠肺炎合并呼吸衰竭患者中非常重要。有两种技术可以支持呼吸衰竭患者。目的:本研究旨在评估重症监护病房(ICU)早期气管切开术患者的护理效果和质量,并比较插管和早期气管切开术的死亡率、住院时间和预后。方法:以某三级医院ICU收治的新冠肺炎确诊患者为研究对象。在研究开始时,所有患者均插管并连接机械呼吸机。在三天内,强化医师随机对一半的患者进行床边经皮扩张性气管切开术(PDT)。早期气管切开术定义为气管插管后3天内进行气管切开术。结果:共纳入36例患者,分为两组,早期气管切开18例,气管插管18例。气管切开术组患者中有一半(50%)从COVID-19呼吸衰竭中恢复并出院。插管组所有患者均已过期。早期气管切开术患者在ICU的生存时间为26.47±3.79天,插管患者为7.58±2.36天。结论:与经气管插管相比,早期气管切开治疗COVID-19呼吸衰竭患者可显著降低病死率。然而,气道管理与早期气管切开术增加住院时间,可以增加恢复。因此,本研究建议尽早行气管切开术。
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The Comparison Between the Early Tracheostomy and Orotracheal Intubation in COVID-19 Patients Required Mechanical Ventilation
Background: Supportive respiratory care and airway management are very important in treating COVID-19 patients with respiratory failure. There are two techniques for supporting patients with respiratory failure. Objectives: The current study aims to evaluate the efficacy and quality of patient care with early tracheostomy in intensive care unit (ICU) and compare mortality, hospital stay, and outcome between intubation and early tracheostomy. Methods: This study is conducted on total patients with confirmed COVID-19 in the ICU centers of a tertiary hospital. At the beginning of the study, all patients were intubated and connected to a mechanical ventilator. Within three days, the intensivists randomly performed bedside percutaneous dilational tracheostomy (PDT) for half of the patients. Early tracheostomy was defined as conducting tracheostomy within three days from intubation. Results: The total number of 36 patients was included in the study and categorized into two groups, including 18 patients in the early tracheostomy and 18 in orotracheal intubation. Half of the patients (50%) in the tracheostomy group were recovered from COVID-19 respiratory failure and discharged from ICU and hospital. All patients in the intubation group were expired. The length of staying alive in ICU in patients with an early tracheostomy was 26.47±3.79 compared with 7.58±2.36 days in intubated patients. Conclusion: The early tracheostomy compared with orotracheal intubation in respiratory failure patients with COVID-19 can significantly decrease mortality. However, airway management with an early tracheostomy increases the hospitalization stay and can increase recovery. So, conducting the early tracheostomy is recommended in this study.
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