用网络方法鉴定宫颈癌关键基因的转录组meta分析

P. Sadeghi, Amir Zarei, M. Sadeghi
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引用次数: 0

摘要

摘要背景与目的:宫颈癌是女性中最常见的癌症之一。复杂疾病的准确诊断和治疗需要精确识别疾病的分子特征。转录组谱为研究细胞的基因表达提供了有价值的信息。应用元分析方法以及基于网络的方法提供了关于研究数据的精确和有价值的信息,可用于开发新的诊断和治疗方法。本研究的目的是利用网络方法对宫颈癌转录组进行荟萃分析,以确定该疾病的关键基因。
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Meta-Analysis of Cervical Cancer Transcriptome with a Network Approach to Identify Key Genes in the Disease
Received: 28 Oct, 2018 Accepted: 11 Dec, 2019 Abstract Background and Objectives: Cervical cancer is one of the most prevalent cancers among women. Accurate diagnosis and treatment of complex diseases require precise identification of molecular characteristics of the disease. Transcriptome profiles provide valuable information on gene expression of the studied cells. Applying metaanalysis approache along with network-based approaches provides precise and valuable information about studied data, which can be used in developing new diagnostic and therapeutic methods. The aim of this study was meta-analysis investigation of cervical cancer transcriptome using a network approach in order to identify key genes in the disease.
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