尼日利亚Jos大学教学医院幽门螺杆菌感染、慢性胃炎和胃黏膜肠化生3例胃癌与胃癌的关系

Kwaghe Bv, N. Ha, Emmmanuel I, Abobarin Oi, Akpa Po, Richards Ks
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引用次数: 0

摘要

背景:1994年,根据流行病学证据,国际癌症研究机构(WHO)将幽门螺杆菌列为1类人类致癌物。随后,Wantabe等人提供了实验证据。这引发了几项关于世界不同地区胃癌患者幽门螺杆菌患病率的研究。在非洲,一些研究报告的各种人群的感染率与这种感染引起的发病率并不平行。目的:探讨幽门螺杆菌感染、慢性胃炎、胃黏膜肠化生与胃癌的关系。方法:回顾性组织病理学研究了2005年1月至2012年12月Jos大学教学医院(JUTH)组织病理学部门观察到的所有伴有癌旁非癌上皮的胃癌。块和档案幻灯片用于
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Relationship between Gastric Cancers and Trio of Helicobacter Pylori Infection, Chronic Gastritis and Gastric Mucosal Intestinal Metaplasia as seen in Jos University Teaching Hospital, Nigeria
Background: In 1994 Helicobacter pylori was classified as class 1 human carcinogen by the IARC (WHO), based on epidemiological evidence. Experimental evidence was subsequently provided by Wantabe et al. This has triggered several studies on the prevalence of H. pylori in patients with Gastric cancers in various regions of the world. In Africa the infection rate in various populations as reported by some studies are not parallel to the incidence of morbidity caused by this infection. Objective: To determine the relationship between Helicobacter pylori infection, Chronic gastritis, Gastric mucosal intestinal metaplasia with Gastric cancers. Methodology: This was a retrospective histopathological study of all gastric cancers with adjacent non – cancerous epithelium seen between January 2005 and December 2012 in the department of Histopathology, Jos University Teaching Hospital (JUTH). Blocks and archival slides were used for the
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