妊娠期天疱疮1例报告

S. Sabir, Z. Sami, N. Youssouf, Safia Gmih, M. Jalal, A. Lamrissi, S. Bouhya
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引用次数: 0

摘要

妊娠相关皮肤病是一个异质性的群体,具有不同的表达,从单纯影响审美的病理到预后不良的病理。天疱疮的发生在怀孕期间是例外。诊断通常很容易,并基于临床,组织学和直接和间接免疫荧光。在这种关联中没有观察到临床生物学特殊性,但母胎并发症的发生使其更加严重。治疗主要以皮质类固醇治疗、血浆置换和静脉注射免疫球蛋白为主。我们报告一例患者,37岁,已婚,是3个活阴道的母亲,就诊于红斑丘疹性病变,与玫瑰花和假玫瑰花病变相关的水泡占据腹部,不考虑脐周区域,四肢全身性下臂和前臂,发生在妊娠晚期,假定无监测怀孕36周闭经3天,皮肤活检支持类天疱疮。
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Gestational Pemphigus : A Case Report
Pregnancy-associated dermatoses represent a heterogeneous group with variable expression, ranging from pathologies with simple aesthetic impact to those with a pejorative prognosis. The occurrence of pemphigus during pregnancy is exceptional. The diagnosis is generally easy and is based on the clinic, histology and direct and indirect immunofluorescence. No clinico-biological particularity is observed during this association, but the occurrence of maternal-fetal complications makes it all the more serious. The treatment is mainly based on corticosteroid therapy, plasmapheresis as well as intravenous immunoglobulins. We report the case of a patient37 years old, married and mother of 3 living vaginally who consults for spots erythemato-papular lesions, vesicular in places associated with lesions in rosette and pseudo-rosette occupying the abdomen without respecting the periumbilical region, the limbs generalized lower arms and forearms occurring in the third trimester in a presumed unmonitored pregnancy at 36 weeks of amenorrhea and 3 days and whose skin biopsy wasin favor of a pemphigoid.
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