Karina E. Hew , Arvind Bakhru , Evan Harrison , Mehmet O. Turan , Ryan MacDonald , Dwight D. Im , Neil B. Rosenshein
{"title":"肥胖对卵巢癌复发时间影响的回顾性研究","authors":"Karina E. Hew , Arvind Bakhru , Evan Harrison , Mehmet O. Turan , Ryan MacDonald , Dwight D. Im , Neil B. Rosenshein","doi":"10.1016/j.cogc.2014.02.002","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction/Background</h3><p>The objective of this study was to examine whether obesity affects the time to recurrence in primary epithelial ovarian cancer.</p></div><div><h3>Patients and Methods</h3><p>A multicenter retrospective chart review was performed between 2004 and 2009. Three hundred seventy patients were eligible for analysis. Demographic and clinicopathological variables and treatment-related data were collected. Women with a body mass index (BMI) > 30 were categorized as obese. The time to recurrence was quantified in terms of months. Survival analyses were performed using the Kaplan-Meier method and compared using log-rank testing.</p></div><div><h3>Results</h3><p>One hundred thirty (35%) obese patients were compared with 240 (65%) nonobese patients. A recurrence was documented in 125 (47.9%) nonobese patients and 49 (37.7%) obese patients. Time to recurrence between both BMI groups was identical, at 15 months (<em>P</em> = 1.0). The progression-free survival was similar in obese and nonobese subjects (<em>P</em> = .118).</p></div><div><h3>Conclusion</h3><p>Obesity does not affect the recurrence time in patients with primary ovarian cancer.</p></div>","PeriodicalId":100274,"journal":{"name":"Clinical Ovarian and Other Gynecologic Cancer","volume":"6 1","pages":"Pages 31-35"},"PeriodicalIF":0.0000,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cogc.2014.02.002","citationCount":"5","resultStr":"{\"title\":\"The Effect of Obesity on the Time to Recurrence in Ovarian Cancer: A Retrospective Study\",\"authors\":\"Karina E. Hew , Arvind Bakhru , Evan Harrison , Mehmet O. Turan , Ryan MacDonald , Dwight D. Im , Neil B. Rosenshein\",\"doi\":\"10.1016/j.cogc.2014.02.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction/Background</h3><p>The objective of this study was to examine whether obesity affects the time to recurrence in primary epithelial ovarian cancer.</p></div><div><h3>Patients and Methods</h3><p>A multicenter retrospective chart review was performed between 2004 and 2009. Three hundred seventy patients were eligible for analysis. Demographic and clinicopathological variables and treatment-related data were collected. Women with a body mass index (BMI) > 30 were categorized as obese. The time to recurrence was quantified in terms of months. Survival analyses were performed using the Kaplan-Meier method and compared using log-rank testing.</p></div><div><h3>Results</h3><p>One hundred thirty (35%) obese patients were compared with 240 (65%) nonobese patients. A recurrence was documented in 125 (47.9%) nonobese patients and 49 (37.7%) obese patients. Time to recurrence between both BMI groups was identical, at 15 months (<em>P</em> = 1.0). The progression-free survival was similar in obese and nonobese subjects (<em>P</em> = .118).</p></div><div><h3>Conclusion</h3><p>Obesity does not affect the recurrence time in patients with primary ovarian cancer.</p></div>\",\"PeriodicalId\":100274,\"journal\":{\"name\":\"Clinical Ovarian and Other Gynecologic Cancer\",\"volume\":\"6 1\",\"pages\":\"Pages 31-35\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2013-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.cogc.2014.02.002\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Ovarian and Other Gynecologic Cancer\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2212955314000246\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Ovarian and Other Gynecologic Cancer","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212955314000246","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The Effect of Obesity on the Time to Recurrence in Ovarian Cancer: A Retrospective Study
Introduction/Background
The objective of this study was to examine whether obesity affects the time to recurrence in primary epithelial ovarian cancer.
Patients and Methods
A multicenter retrospective chart review was performed between 2004 and 2009. Three hundred seventy patients were eligible for analysis. Demographic and clinicopathological variables and treatment-related data were collected. Women with a body mass index (BMI) > 30 were categorized as obese. The time to recurrence was quantified in terms of months. Survival analyses were performed using the Kaplan-Meier method and compared using log-rank testing.
Results
One hundred thirty (35%) obese patients were compared with 240 (65%) nonobese patients. A recurrence was documented in 125 (47.9%) nonobese patients and 49 (37.7%) obese patients. Time to recurrence between both BMI groups was identical, at 15 months (P = 1.0). The progression-free survival was similar in obese and nonobese subjects (P = .118).
Conclusion
Obesity does not affect the recurrence time in patients with primary ovarian cancer.
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