异位自体角膜移植术中RGP晶状体作为临时角膜假体的应用

Allurie Umel, Richmond Siazon, M. F. de la Paz
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摘要

介绍异位自体角膜移植术和ECCE联合后房型人工晶状体(IOL)植入术的病例,并证明RGP晶状体作为一种安全、经济的临时角膜假体替代方法的新应用。65/F患者表现为失明,青光眼OS但角膜清晰,角膜失代偿伴白内障,视觉电位良好。由于角膜异体移植的稀缺性和病例的高危性,我们进行了异位自体角膜移植术,由于晶状体混浊,我们在OD中植入了ECCE和IOL。临时角膜假体(TKP)(如Eckardt和Landers模型)由于较低的成本和可及性而被RGP取代。在巩膜上水平和垂直位置预先放置两个聚乳酸垂直床垫缝合线,并松开缝合线。接下来,使用8mm真空环钻进行左侧角膜穿刺术,随后注入眼粘手术装置(OVD)并将直径10mm的RGP晶状体放置在左侧开放的球体上,通过绑好预先放置的交叉缝线来固定。然后,使用类似大小的环钻进行右角膜穿刺术。采用开窗技术摘出白内障,人工晶状体袋内植入术。然后将清晰的左侧角膜扣移植到OD,反之亦然。术后,VA从手部运动改善到10/200(第1天)。术后4周移植物保持清晰,VA进一步改善。IOP维持在15 mmHg以下。异位自体角膜移植术是单侧角膜失明患者的一种有效选择。这在角膜移植费用昂贵的国家是有用的,特别是在大流行期间角膜异体移植稀缺。根据我们的经验,使用RGP晶状体作为临时角膜假体的一种安全、经济的替代方法是安全的。
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Use of RGP lens as Temporary Keratoprosthesis in Open-Sky Technique for Heterotopic Autokeratoplasty
To present a case of a combined procedure of heterotopic autokeratoplasty and ECCE with posterior chamber intraocular lens (IOL) implantation, and to demonstrate the novel use of an RGP lens as a safe, cost-effective alternative to temporary keratoprosthesis. A 65/F presented with blindness, OS from glaucoma but with a clear cornea, and corneal decompensation with cataract in OD with good visual potential. Heterotopic autokeratoplasty was performed due to the scarcity of corneal allografts and the high-risk nature of the case, with ECCE and IOL implantation in OD due to lens opacity. Temporary keratoprosthesis (TKP) (such as Eckardt and Landers models) was substituted with RGP due to lower cost and accessibility. Pre-placement of two polyglactin perpendicular mattress sutures in the episclera at the horizontal and vertical positions was done and left untied. Next, left corneal trephination was performed using an 8-mm vacuum trephine, followed by the instillation of oculoviscosurgical device (OVD) and placement of a 10-mm diameter RGP lens over the left open globe, secured in place by tying the pre-placed overlying cross sutures. Then, right corneal trephination using a similar-sized trephine proceeded. Cataract was extracted in open-sky technique with IOL in the bag implantation. The clear left corneal button was then transplanted to OD and vice-versa. Postoperatively, VA improved from hand motions to 10/200 (Day 1). The graft remained clear 4 weeks post-op with further improvement in VA. IOP was maintained below 15 mmHg. Heterotopic autokeratoplasty is a valid option for unilateral cornea blind patients who have clear corneas in the fellow eye with no visual potential. This is useful in countries where corneal transplantation is costly, especially during time of pandemic when corneal allografts are scarce. In our experience, it can be safely performed using an RGP lens as a safe and cost-effective alternative to temporary keratoprosthesis.
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