{"title":"希夫碱衍生物在金属离子检测中的医学意义及化学传感应用综述","authors":"Meshal Alshamrani","doi":"10.3233/mgc-220091","DOIUrl":null,"url":null,"abstract":"Schiff bases, named after Hugo Schiff, are formed when primary amine reacts with carbonyl compounds (aldehyde or ketone) under specific conditions. Schiff bases are economical, simple synthetic routes, and easily accessible in laboratories. They have medicinal and biological applications such as antiviral, antioxidant, antifungal, anticancer, anthelmintic, antibacterial, antimalarial, anti-inflammatory, antiglycation, anti-ulcerogenic, and analgesic potentials. A number of Schiff bases are reported for the detection of various metal ions. They are also used as catalysts, polymer stabilizers, intermediates in organic synthesis, and corrosion inhibitors. In this review, we have highlighted the recent advancements in the development of bioactive Schiff base derivatives and their sensing applications for detecting metal cations. Additionally, various spectroscopic techniques for structural characterization, such as X-ray diffraction analysis (XRD), FT-IR, UV-vis, and NMR spectroscopy were also discussed.","PeriodicalId":18027,"journal":{"name":"Main Group Chemistry","volume":"27 1","pages":""},"PeriodicalIF":1.3000,"publicationDate":"2022-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Medicinal importance and chemosensing applications of Schiff base derivatives for the detection of metal ions: A review\",\"authors\":\"Meshal Alshamrani\",\"doi\":\"10.3233/mgc-220091\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Schiff bases, named after Hugo Schiff, are formed when primary amine reacts with carbonyl compounds (aldehyde or ketone) under specific conditions. Schiff bases are economical, simple synthetic routes, and easily accessible in laboratories. They have medicinal and biological applications such as antiviral, antioxidant, antifungal, anticancer, anthelmintic, antibacterial, antimalarial, anti-inflammatory, antiglycation, anti-ulcerogenic, and analgesic potentials. A number of Schiff bases are reported for the detection of various metal ions. They are also used as catalysts, polymer stabilizers, intermediates in organic synthesis, and corrosion inhibitors. In this review, we have highlighted the recent advancements in the development of bioactive Schiff base derivatives and their sensing applications for detecting metal cations. Additionally, various spectroscopic techniques for structural characterization, such as X-ray diffraction analysis (XRD), FT-IR, UV-vis, and NMR spectroscopy were also discussed.\",\"PeriodicalId\":18027,\"journal\":{\"name\":\"Main Group Chemistry\",\"volume\":\"27 1\",\"pages\":\"\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2022-11-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Main Group Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.3233/mgc-220091\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Main Group Chemistry","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.3233/mgc-220091","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Medicinal importance and chemosensing applications of Schiff base derivatives for the detection of metal ions: A review
Schiff bases, named after Hugo Schiff, are formed when primary amine reacts with carbonyl compounds (aldehyde or ketone) under specific conditions. Schiff bases are economical, simple synthetic routes, and easily accessible in laboratories. They have medicinal and biological applications such as antiviral, antioxidant, antifungal, anticancer, anthelmintic, antibacterial, antimalarial, anti-inflammatory, antiglycation, anti-ulcerogenic, and analgesic potentials. A number of Schiff bases are reported for the detection of various metal ions. They are also used as catalysts, polymer stabilizers, intermediates in organic synthesis, and corrosion inhibitors. In this review, we have highlighted the recent advancements in the development of bioactive Schiff base derivatives and their sensing applications for detecting metal cations. Additionally, various spectroscopic techniques for structural characterization, such as X-ray diffraction analysis (XRD), FT-IR, UV-vis, and NMR spectroscopy were also discussed.
期刊介绍:
Main Group Chemistry is intended to be a primary resource for all chemistry, engineering, biological, and materials researchers in both academia and in industry with an interest in the elements from the groups 1, 2, 12–18, lanthanides and actinides. The journal is committed to maintaining a high standard for its publications. This will be ensured by a rigorous peer-review process with most articles being reviewed by at least one editorial board member. Additionally, all manuscripts will be proofread and corrected by a dedicated copy editor located at the University of Kentucky.