微胶囊化:大蒜(Allium sativum)粉末的味道和气味掩盖方法

S. Gondal, N. Abbas, A. Hussain
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引用次数: 1

摘要

本研究的目的是制备一种方便的大蒜粉配方,通过抑制其特征气味和掩盖味道来提高用户的依从性。采用溶剂蒸发法制备大蒜粉微胶囊。通过对10名健康人体志愿者进行的单盲交叉研究,结果显示出>80%的产率,>70%的载药效率和缓释特性(有望持续作用超过2小时),并显着降低了芳香气味和味觉。
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Microencapsulation: A taste and odour masking approach for garlic (Allium sativum) powder
The purpose of this study was to prepare a convenient formulation of garlic powder which has enhanced user compliance by suppressing its characteristic odour and masking the taste. Microcapsules of garlic powder were formulated by solvent evaporation method. Results show >80% yield, >70% drug loading efficiency and slow release profile (promising sustained action for more than 2hrs) and a significant reduction in the aromatic smell and taste evaluated through a single blind cross-over study conducted using ten healthy human volunteers.
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