Sachin Vanpure, Nishant Nandkhile, R. Bhondwe, Suresh Palve
{"title":"海棠叶甲醇提取物中植物化学物质的光谱分析及ADME预测","authors":"Sachin Vanpure, Nishant Nandkhile, R. Bhondwe, Suresh Palve","doi":"10.52711/0975-4385.2022.00041","DOIUrl":null,"url":null,"abstract":"Phytochemicals are biologically active compounds found in plants. Phytochemicals of medicinal plant can cure various diseases thus phytochemical screening of plants is necessary for the discovery and devlopment of therapeutic agents. In present study. The FTIR spectrum of crude extract confirmed the presence of alkanes, carboxylic acid, alcohol, aromatics and esters. The HPLC analysis of methanolic extract shows 11 peaks at 254nm, it may be phenolic and alcoholic compounds. The plant extract was scanned by using UV-VIS spectrophotometer ranging from 200-700nm and characteristic peaks were detected with different absorption respectively. The ADME study particularly focuses on important properties like lipophilicity, water solubility, pharmacokinetic, drug likeness, medicinal chemistry and this study carried out by using insilico ADME tool called Swiss ADME.","PeriodicalId":21071,"journal":{"name":"Research Journal of Pharmacognosy and Phytochemistry","volume":"16 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Spectroscopic Analysis and ADME prediction of Phytochemicals in Methanolic Leaves Extract of Avicennia marina\",\"authors\":\"Sachin Vanpure, Nishant Nandkhile, R. Bhondwe, Suresh Palve\",\"doi\":\"10.52711/0975-4385.2022.00041\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Phytochemicals are biologically active compounds found in plants. Phytochemicals of medicinal plant can cure various diseases thus phytochemical screening of plants is necessary for the discovery and devlopment of therapeutic agents. In present study. The FTIR spectrum of crude extract confirmed the presence of alkanes, carboxylic acid, alcohol, aromatics and esters. The HPLC analysis of methanolic extract shows 11 peaks at 254nm, it may be phenolic and alcoholic compounds. The plant extract was scanned by using UV-VIS spectrophotometer ranging from 200-700nm and characteristic peaks were detected with different absorption respectively. The ADME study particularly focuses on important properties like lipophilicity, water solubility, pharmacokinetic, drug likeness, medicinal chemistry and this study carried out by using insilico ADME tool called Swiss ADME.\",\"PeriodicalId\":21071,\"journal\":{\"name\":\"Research Journal of Pharmacognosy and Phytochemistry\",\"volume\":\"16 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-11-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Research Journal of Pharmacognosy and Phytochemistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.52711/0975-4385.2022.00041\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Research Journal of Pharmacognosy and Phytochemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.52711/0975-4385.2022.00041","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Spectroscopic Analysis and ADME prediction of Phytochemicals in Methanolic Leaves Extract of Avicennia marina
Phytochemicals are biologically active compounds found in plants. Phytochemicals of medicinal plant can cure various diseases thus phytochemical screening of plants is necessary for the discovery and devlopment of therapeutic agents. In present study. The FTIR spectrum of crude extract confirmed the presence of alkanes, carboxylic acid, alcohol, aromatics and esters. The HPLC analysis of methanolic extract shows 11 peaks at 254nm, it may be phenolic and alcoholic compounds. The plant extract was scanned by using UV-VIS spectrophotometer ranging from 200-700nm and characteristic peaks were detected with different absorption respectively. The ADME study particularly focuses on important properties like lipophilicity, water solubility, pharmacokinetic, drug likeness, medicinal chemistry and this study carried out by using insilico ADME tool called Swiss ADME.