孜然籽油提取物作为口腔表面消毒剂的效果评价

M. Moaddeli, A. Araghizadeh, E. Shabani
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摘要

简介:孜然(Nigella Sativa)籽油提取物中含有抗菌成分。孜然精油具有抗菌作用,对不同类型的革兰氏阴性和革兰氏阳性细菌以及病毒、寄生虫和真菌都有影响。本研究旨在探讨孜然提取物在口腔表面消毒中的抗菌性能。材料与方法:本研究采用实验方法,分为孜然提取物组、去甲素组和对照组。每组配制12种培养基,分别对24小时和48小时产生的菌落进行计数,采用SPSS软件和t检验评估显著性水平。结果:24h时,孜然籽油提取液培养皿细菌菌落计数为5.83,decex培养皿细菌菌落计数为0。在48小时,也有显著的差异,因为孜然(Nigella Sativa)油提取物的培养皿上的细菌菌落计数太多而无法计数,而用Deconex的培养皿上的细菌菌落计数为0.83。结论:小茴香籽油提取物不适合作为口腔表面孤独的替代消毒剂。但它的一些成分,如百里醌和对苯二酚,可以用来生产消毒液。
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Evaluation of the Effectiveness of Cumin (Nigella Sativa) Seed Oil Extract as an Alternative Disinfectant of Dental Surfaces
Introduction: Cumin (Nigella Sativa) seed oil extract has some ingredients which have antimicrobial effects. The essential oils present in cumin act as antimicrobial agent and it influence on different type of Gram-negative and Gram-positive bacteria and also viruses, parasites and fungi. This study aimed to investigate the antimicrobial properties of cumin extract in disinfecting dentistry surfaces. Material and Methods: This study was performed experimentally and had three groups of cumin extract, Deconex and control group. For each of these groups, 12 culture media were prepared and we counted the colonies created in 24 hours and 48 hours and significance level was assessed using SPSS software and t-test.    Results: At 24 hours, there was a significant difference between the bacterial colony counts of the petri dishes from Cumin Seed (Nigella Sativa) Oil Extract at 5.83 and the Deconex at 0. And at 48 hours, there was also a significant difference since the bacterial colony count on the petri dishes with Cumin (Nigella Sativa) Oil Extract was too many to count and a 0.83 bacterial colony count for the petri dishes with the Deconex. Conclusion: The Cumin (Nigella Sativa) seed oil extract is not suitable to use as an alternative disinfectant of dental surfaces lonely. But some of its ingredients such as thymoquinone and hydroquinone can be used to produce a disinfecting solution.
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