{"title":"聚合酶链反应在莱姆病诊断中的应用","authors":"J. Gutiérrez , M.A. Rodriguez , M.C. Maroto","doi":"10.1016/0888-0786(95)97893-A","DOIUrl":null,"url":null,"abstract":"<div><p>Molecular diagnosis of Lyme disease is hindered by genetic variability and, in genes that have a certain degree of stability, by the presence of identical regions in other genera in both related and unrelated species. There are therefore certain limitations in genetic diagnostic techniques and as yet no definitive laboratory diagnostic technique has been discovered.</p></div>","PeriodicalId":101161,"journal":{"name":"Serodiagnosis and Immunotherapy in Infectious Disease","volume":"7 3","pages":"Pages 109-113"},"PeriodicalIF":0.0000,"publicationDate":"1995-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0888-0786(95)97893-A","citationCount":"1","resultStr":"{\"title\":\"Applications of polymerase chain reaction to diagnose lyme borreliosis\",\"authors\":\"J. Gutiérrez , M.A. Rodriguez , M.C. Maroto\",\"doi\":\"10.1016/0888-0786(95)97893-A\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Molecular diagnosis of Lyme disease is hindered by genetic variability and, in genes that have a certain degree of stability, by the presence of identical regions in other genera in both related and unrelated species. There are therefore certain limitations in genetic diagnostic techniques and as yet no definitive laboratory diagnostic technique has been discovered.</p></div>\",\"PeriodicalId\":101161,\"journal\":{\"name\":\"Serodiagnosis and Immunotherapy in Infectious Disease\",\"volume\":\"7 3\",\"pages\":\"Pages 109-113\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1995-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0888-0786(95)97893-A\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Serodiagnosis and Immunotherapy in Infectious Disease\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/088807869597893A\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Serodiagnosis and Immunotherapy in Infectious Disease","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/088807869597893A","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Applications of polymerase chain reaction to diagnose lyme borreliosis
Molecular diagnosis of Lyme disease is hindered by genetic variability and, in genes that have a certain degree of stability, by the presence of identical regions in other genera in both related and unrelated species. There are therefore certain limitations in genetic diagnostic techniques and as yet no definitive laboratory diagnostic technique has been discovered.