核医学中与常用多模式检查相关的有效剂量

C. Camacho López , J.F. Martí Vidal , M. Falgás Lacueva , J.L. Vercher Conejero
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引用次数: 3

摘要

目的了解核医学常用的多模式程序,即单光子发射断层扫描和正电子发射断层扫描,结合计算机断层扫描、SPECT/CT和PET/CT可给予的有效剂量(E)。有效剂量将根据本底等效辐射时间(BERT)表示,CT扫描对总剂量的贡献也将进行研究。材料与方法每道程序的有效剂量均计算为外照射剂量(CT部分)与内照射剂量(放射药物给药)之和。通过广泛的文献检索收集了双方的资料。结果给出了各手术的最小和最大有效剂量[Emin, Emax]范围。这些剂量范围为0.5至49.1毫西弗。BERT从2.6个月到20.4年不等。CT对总有效剂量的贡献从2.1%到93%不等,根据图像采集方案及其目的而定。与用于衰减校正和解剖定位的CT采集剂量相比,进行诊断性CT扫描的剂量增加了4.3倍。本文着重讨论多模态程序中可给出的有效剂量水平,同时考虑到这些数据是不断变化的,应定期更新。当增加CT扫描时,了解剂量学影响是很重要的。根据研究的适应症应用优化的方案减少了患者的暴露而不丢失重要信息。
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Effective Doses Associated with the Usual Multimodal Examinations in Nuclear Medicine

Objective

To know the effective doses (E) that can be given in the common multimodal procedures in nuclear medicine, single photon emission tomography and positron emission tomography, combined with computed tomography, SPECT/CT and PET/CT. Effective dose will be expressed according to background equivalent radiation time (BERT) and the contribution of the CT scan to the total dose will also be studied.

Material and methods

The effective dose of each procedure has been calculated as the sum of the external radiation dose (CT part) and the internal one (radiopharmaceutical administration). Data from each side were collected through extensive literature search.

Results

A range of minimum and maximum effective doses [Emin, Emax] associated with each procedure is shown. These doses range from 0.5 to 49.1 mSv. BERT ranges from 2.6 months to 20.4 years. The CT contribution to the total effective dose varies from 2.1% to 93%, according to the image acquisition protocol and its purpose. Performing a diagnostic CT scan increases the dose up to a factor of 4.3 times compared to the dose used for CT acquisition for attenuation correction and anatomic localization.

Conclusions

This article focuses on the effective dose level that can be given in multimodal procedures, bearing in mind that the data are subject to constant changes and should be updated periodically. It is important to know the dosimetric impact when the CT scan is added. The application of optimized protocols according to the indication of the study reduces patient's exposure without loss of significant information.

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