我们是否意识到高磷血症对儿童重症患者的死亡率和发病率的影响与低磷血症一样大?

Y. Akbaş, A. Koker, N. Erkek
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引用次数: 2

摘要

目的:低磷血症先前被证明会影响儿科重症监护期间的入院时间、机械呼吸机需求、死亡率和发病率。与以往的研究不同,我们的研究旨在揭示高磷血症是否与低磷血症一样影响儿科重症患者的发病率和死亡率。方法记录患者的年龄、性别、入院原因、基础疾病、入院时、1-4天、5-10天检查的磷水平、机械通气时间、住院时间、最终状态及入院前24 h计算的PRISM和PELOD评分。结果低磷血症和高磷血症患者的死亡率明显高于正常磷血症患者。死亡率最高的是那些在5-10天出现高磷血症的患者。入院时各组患者的PELOD评分差异有统计学意义(p:0.04)。结论:在我们的研究中,我们发现高磷血症与低磷血症对于入住PICU的患者来说是一个严重的问题。入院时确诊为高磷血症的患者PELOD评分明显较高。高磷血症在PELOD评分上的显著差异是我们研究的重点之一。不应忘记,像低磷血症一样,高磷血症可能会对儿科重症监护患者造成严重问题。
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Are We Aware that Hyperphosphatemia Affects Mortality and Morbidity as much as Hypophosphatemia in Pediatric Intensive Care Patients?
OBJECTIVE Hypophosphatemia was previously shown to affect the duration of admission, mechanical ventilator requirements, mortality and morbidity during pediatric intensive care. Different from previous studies, our study was planned with the aim of showing whether hyperphosphatemia affects morbidity and mortality in pediatric intensive care patients as much as hypophosphatemia. METHOD Patients' ages, genders, reason for admission, underlying diseases, phosphorus levels examined on admission and on the 1-4th and 5-10th-days, duration on mechanical ventilation, duration of admission, final status and PRISM and PELOD scores calculated in the first 24 hours of admission were recorded. RESULTS Mortality was distinctly higher for those who were hypophosphatemic and hyperphosphatemic compared to those who were normophosphatemic. The highest mortality was identified in those who were hyperphosphatemic on the 5-10th-days. PELOD scores were only significantly different according to admission phosphorus levels (p:0.04). CONCLUSION In our study, we identified that hyperphosphatemia is a serious problem as hypophosphatemia for patients who admitted to the PICU. Patients identified to be hyperphosphatemic on admission had a significantly higher PELOD score. The significant difference of hyperphosphatemia in terms of PELOD score is one of the important points shown in our study. It should not be forgotten that like hypophosphatemia, hyperphosphatemia may cause serious problems in pediatric intensive care patients.
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Pediatric endocrinology reviews : PER
Pediatric endocrinology reviews : PER Medicine-Endocrinology, Diabetes and Metabolism
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期刊介绍: PEDIATRIC ENDOCRINOLOGY REVIEWS (PER) publishes scholarly review articles in all areas of clinical and experimental Endocrinology, Diabetes, Nutrition and Metabolism. PER is intended for practicing pediatricians, pediatric endocrinologists, pediatric diabetologists, pediatric gastroenterologists, neonatologists, pediatric gynecologists, nutritionists, sport physicians and pediatricians-in-training. PER will also publish topics on specific subjects or as proceedings of scientific meetings in the above fields of interest. All articles, whether invited or direct contributions, are peer-reviewed. PER publishes correspondence, book reviews, a meeting calendar and meeting reports.
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