金黄色葡萄球菌多重耐药基因的流行与传播。

T. Chakraborty, B. Patra, Sutripto Ghosh
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引用次数: 1

摘要

抗生素是一种抗微生物物质,通常用于治疗人类、动物和鱼类,也用于研究各种细菌的敏感性模式。随着疾病数量的增加和新感染的出现,许多用于人类、动物、鱼类和植物的药物正在开发中。然而,随着药物的发展,出现了一种被称为耐药性的现象,这使全世界的科学家和研究人员感到震惊。在编码特定药物、质粒或转座子的基因中建立耐药性、多药外排泵的作用、染色体基因的变化或葡萄球菌盒染色体都可以产生耐药性。金黄色葡萄球菌是最常见的革兰氏阳性细菌,具有多重耐药表型,揭示了其致病性。葡萄球菌具有多种可传播的基因,使它们对抗生素等治疗产生抗药性。亚历山大·弗莱明(Alexander Fleming)发现的抗生素长期以来一直是对抗细菌性疾病的福音。由于抗生素的过度使用和不合理使用,出现了耐药细菌,引起了全世界科学家的关注。因此,作为对抗耐药细菌的第一步,很明显需要广泛的努力来遏制抗生素的滥用。本文综述了金黄色葡萄球菌中不同耐多药基因的流行及传播情况。
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Prevalence and Transmission of multi drug resistance gene in Staphylococcus aureus.
Antibiotics are antimicrobial substances that are commonly used to treat humans, animals, and fish, as well as to research susceptibility patterns in a variety of bacteria. With the rising number of diseases and the emergence of new infections, many drugs for humans, animals, fish, and plants are being developed. However, with the development of pharmaceuticals came the advent of a phenomenon known as drug resistance, which has alarmed scientists and researchers all around the world. The building of resistance in genes that code for specific drugs, plasmids, or transposons, the action of multidrug efflux pumps, changes in chromosomal genes, or the Staphylococci cassette chromosome can all produce it. Staphylococcus aureus, the most common Gram-positive bacteria, has a multidrug-resistant phenotype that reveals its pathogenicity. Staphylococcus sp. possesses a variety of transmissible genes that cause them to be resistant to treatments such as antibiotics. The discovery of antibiotics by Alexander Fleming has long been a boon in the fight against bacterial illnesses. Drug-resistant bacteria have emerged as a result of antibiotic overuse and suboptimal usage, attracting the attention of scientists throughout the world. Therefore, as a first step in combating drug-resistant bacteria, it is obvious that widespread efforts to curb antibiotic abuse are required. This review focuses on and brings to society the prevalence of different multidrug resistant genes in Staphylococcus aureus and their transmission.
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