头颈部动静脉畸形治疗后复发

IF 0.4 Q4 MEDICINE, RESEARCH & EXPERIMENTAL AIMS Medical Science Pub Date : 2022-01-01 DOI:10.3934/medsci.2022003
Do Thi Ngoc Linh, Lâm Khánh, L. Dung, Nguyen Hong Ha, Tran Cao Son, N. M. Duc
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引用次数: 0

摘要

目的动静脉畸形(AVMs)是一种易复发的侵袭性疾病。AVM的治疗是复杂的,特别是在解剖学上困难的头颈部区域。本研究分析颅外头颈部AVM表现与复发率的相关性。方法回顾性分析2008年1月至2015年12月55例经栓塞切除的头颈部AVM患者的AVM复发情况。复发被定义为栓塞和切除后AVM扩张的任何证据。检查患者变量,包括性别、年龄、AVM大小、AVM位置、分期和治疗方式,以确定与头颈部AVM复发的相关性。采用SPSS 20.0进行统计学分析。结果本研究共纳入55例AVM栓塞手术切除后随访至少6个月的患者。随访期间,55例患者中有14例复发,长期复发率为25.5%。性别、分期、AVM大小和治疗方式被确定为复发的独立预测因素。低期或较小病灶治疗后复发的可能性较低,且与年龄或部位无关。结论头颈部savms因其复发风险高,是最具挑战性的疾病之一。早期全切除是预防复发的最佳方法。
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Recurrence after treatment of arteriovenous malformations of the head and neck
Objective Arteriovenous malformations (AVMs) are aggressive diseases with a high tendency to recur. AVM treatment is complex, especially in the anatomically difficult head and neck region. This study analyzed correlations between extracranial head and neck AVM presentations and the frequency of recurrence. Methods We retrospectively assessed AVM recurrence among 55 patients with head and neck AVMs treated with embolization and resection between January 2008 and December 2015. Recurrence was defined as any evidence of AVM expansion following embolization and resection. Patient variables, including sex, age, AVM size, AVM location, stage, and treatment modalities, were examined for correlations with the recurrence of head and neck AVMs. Statistical analysis was performed using SPSS 20.0. Results A total of 55 patients with at least 6 months of follow-up following AVM treatment with embolization and surgical resection were enrolled in this study. During follow-up, 14 of 55 patients experienced recurrence (the long-term recurrence rate was 25.5%). Sex, stage, AVM size, and treatment modality were identified as independent predictors of recurrence. Recurrence was less likely following the treatment of lower-stage or smaller lesions and did not correlate with age or location. Conclusions AVMs of the head and neck are among the most challenging conditions to manage due to a high risk of recurrence. Early and total AVM resection is the best method for preventing recurrence.
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来源期刊
AIMS Medical Science
AIMS Medical Science MEDICINE, RESEARCH & EXPERIMENTAL-
自引率
14.30%
发文量
20
审稿时长
12 weeks
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