PET-XPAD3/CT系统正电子发射层析成像空间分辨率的确定

H. O. Dávila, S. M. Ovalle, H. Perez, H. Castro
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引用次数: 2

摘要

以美国国家电气制造商协会(NEMA)为基础,利用AMINE软件构建正弦图,利用22Na正电子发射源,计算了CCPM实验室制作的CLEAR PET-XPAD3/CT小动物样机中正电子发射层析成像仪光电探测器环形阵列系统的空间分辨率。ImXgam课课组负责该项目。将活度约为9 MBq、直径为0.57mm的球形22Na放射源浸入位于层析成像系统几何中心的有机玻璃圆盘中,层析成像系统轴向和横向视场为35 mm。在三个直角轴上对放射源进行位移,并重建每个轴的正弦图。正弦图的形状可以描述每个探测器的正确位置和最大效率。随后,在三个空间轴的每一个轴上进行扫描,扫描的距离足以覆盖放射源的尺寸。记录每个光电探测器的数据。对其他轴重复此过程,然后以视场为中心对放射源进行置中,计算半最大全宽(FWHM)和十分之一最大全宽(FWTM)值,并对其进行抛物线拟合统计,后者设置可获得系统空间分辨率参数。
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Determination of Spatial Resolution of Positron Emission Tomograph of Clear PET-XPAD3/CT System
Based on The National Electrical Manufacturers Association (NEMA), using the AMINE software to construction of sinograms and using a positron emission source of 22Na, were made calculations to determine the spatial resolution of a ring array system of phoswich detectors of positron emission tomograph included in the CLEAR PET-XPAD3/CT prototype for small animals, made in the laboratories of CCPM and whose project is led by the research group ImXgam. The radioactive source 22Na of approximately 9 MBq of activity, with spherical shape and diameter of 0.57mm is immersed in a plexiglas disc that was located at the geometric center of tomographic system with a Field of View (FOV) of 35 mm in the axial and transverse directions. Displacements of radioactive source were performed on the three cartesian axes and was rebuilt a sinogram for each axis. The shape of sinogram allows describe the correct position and the maximum efficiency of each detector. Subsequently, was carried out a scanning in each one of three spatial axes taking enough distance to cover the dimensions of radioactive source. Data for each phoswich detector were recorded. The process was repeated for other axes and then radioactive source was centered with respect to the FOV and were calculated FWHM (Full Width at Half Maximum) and FWTM (Full Width at Tenth Maximum) values and performing statistics of these values with parabolic fitting, the latter setting allows to obtain parameters of spatial resolution of system.
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