用患者自身血浆制备纤维连接蛋白滴眼液的自动装置的评价。

H. Yoshida, Kaori Tsubone, R. Yamashita, Yasuaki Ohtsubo, T. Ishimitsu, A. Kamiya
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引用次数: 0

摘要

据报道,纤维连接蛋白(FN)对角膜营养性溃疡的治疗有效,但FN滴眼液的制备并不是一种简单的技术。我们之前开发了一种使用患者自身血浆制备FN滴眼液的自动装置(Yoshida等人)。日本。J. hospp . pharmacy;, 24, 493-498(1998))。本研究的目的是评估这种自动装置的效率。采用明胶偶联Sepharose 4b (GS 4b)和Sephadex G-25 (PD-10),采用自动装置或手工工艺制备健康人血浆FN滴眼液,测定滴眼液中FN的平均浓度和回收率
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Evaluation of an Automatic Device to Prepare Fibronectin Eyedrops Using a Patient's Own Plasma.
Fibronectin (FN) has been reported to be effective for the treatment of corneal trophic ulcers, but the FN eyedrop preparation is not a simple technique. We previously developed an automatic device to prepare FN eyedrops using a patient's own plasma (Yoshida et al. Jpn. J. Hosp. Pharm., 24, 493-498 (1998)). The aim of this study was to evaluate the efficiency of this automatic device. FN eyedrops were prepared using plasma from healthy individuals either with an automatic device or a manual process using gelatin-coupled Sepharose 4 B (GS 4 B) and Sephadex G-25 (PD-10), The average FN concentration and the recovery rate in the eyedrops
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