2020年4月纽约州切芒县COVID-19预报

Timothy Snyder, Emily A. Eshraghian
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摘要

我们使用基于agent的建模方法来预测美国纽约州Chemung县COVID-19爆发的范围。2020年3月21日,车蒙县出现首例确诊病例。在宣布第一例确诊病例之前,采取了各种缓解措施;与纽约其他地区相比,这使疾病负担保持在较低水平。使用基于主体的建模技术,我们模拟了一次暴发,以估计总感染和死亡人数,以及高峰住院日期和人口普查。这个随机模型用于给agent(车芒县人)分配各种属性,并模拟这些agent在不同时间点的相互作用。模型模拟共256次;这些观察结果用于编制关键结果。图A显示了我们对暴露(橙色)、疾病(红色)、康复(绿色)、住院(蓝色)和死亡(黑色)模拟的平均值、第95和第5百分位累积值的预测。图B展示了我们对医院普查的预测,突出了平均值。我们预计在车芒县总共有312例(90% CI: 106,784)合并诊断和未诊断病例,19例(90% CI: 10,33)高峰医院普查,9例(90% CI: 2,28)总死亡。我们的模型显示,住院高峰日期将出现在2020年4月17日(90%置信区间:4月5日和5月16日)。值得注意的是,由于差异和缺乏可用数据,这些估计数不包括当地辅助生活设施的数据。随着国家强制居家令的持续执行,我们预计,如果辅助生活设施等其他来源对总数的贡献不大,车芒县的医疗资源可以满足因COVID-19而增加的需求。我们对车芒县的分析可以作为农村地区建模的一个例子,可以为医院管理人员和地方官员在资源分配和临床操作方面做出关键的、时间敏感的决策提供信息。
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COVID-19 Forecast for Chemung County, NY, April 2020
We used an agent-based modeling approach to predict the scope of the COVID-19 outbreak in Chemung County, NY, USA. Chemung County’s first confirmed case was on March 21, 2020. A variety of mitigation efforts were placed prior to announcement of the first confirmed case; this has kept the burden of disease low, in contrast to other areas of New York. Using an agent-based modeling technique, we simulated an outbreak in order to estimate the expected number of total infections and deaths, and the peak hospitalization date and census. This stochastic model is used to assign various attributes to agents (people of Chemung County) and simulate interaction between these agents at various time points. The model simulation took place 256 times; these observations were used to compile key outcomes. Panel A presents our predictions for cumulative values at the mean, 95th, and 5th percentile of the simulations for Exposures (Orange), Illnesses (Red), Recoveries (Green), Hospitalizations (Blue), and Deaths (Black). Panel B presents our predictions for Hospital Census, with a highlight of the mean. We expect there to be a total of 312 (90% CI: 106, 784) combined diagnosed and undiagnosed cases, 19 (90% CI: 10, 33) peak hospital census, and 9 (90% CI: 2, 28) total deaths in Chemung County. Our model indicates the peak hospitalization date to occur on April 17, 2020 (90% CI: April 5, May 16). It is important to note that these estimates do not include data from local assisted living facilities, due to variance and lack of available data. With the continued enforcement of the state-mandated stay-at-home order, we expect that Chemung County health care resources can accommodate the increase in need due to COVID-19, provided other sources such as assisted living facilities do not contribute significantly to the totals. Our analysis of Chemung County serves as an example for modeling rural areas and can inform critical, time-sensitive decisions made by hospital administrators and local officials regarding resource allocation and clinical operation.
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