{"title":"小儿免疫性血小板减少性紫癜合并COVID-19病例报告","authors":"Sultan Aydın, Gizem Gülten Altinkaynak","doi":"10.29011/2575-825x.100096","DOIUrl":null,"url":null,"abstract":"Immune Thrombocytopenic Purpura (ITP) of childhood is identified as isolated thrombocytopenia. While it can be triggered by a viral infection such as hepatitis B, hepatitis C, cytomegalovirus, Epstein-Barr, influenza, herpes, varicella-zoster, and HIV or other immune causes, the reason for ITP remains unknown in most patients. We reported a pediatric case with ITP whose COVID-19 total antibody test was positive. Despite the poor response of high dose intravenous immunoglobulin (IVIG), steroid treatment generated a good result. Our patient had an asymptomatic Severe Acute Respiratory Syndrome Coronavirus 2, SARSCoV-2 infection (COVID-19 infection) and COVID-19 PCR was negative. Since we are in the period of the COVID-19-related pandemic, SARS-CoV-2 should be kept in mind in the etiology of ITP. This case raises awareness of both PCR and antibody screening for COVID-19 in patients with ITP, especially in the pandemic season.","PeriodicalId":8302,"journal":{"name":"Archives of pediatrics","volume":"102 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"A Pediatric Case Report with Immune Thrombocytopenic Purpura Associated with COVID-19\",\"authors\":\"Sultan Aydın, Gizem Gülten Altinkaynak\",\"doi\":\"10.29011/2575-825x.100096\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Immune Thrombocytopenic Purpura (ITP) of childhood is identified as isolated thrombocytopenia. While it can be triggered by a viral infection such as hepatitis B, hepatitis C, cytomegalovirus, Epstein-Barr, influenza, herpes, varicella-zoster, and HIV or other immune causes, the reason for ITP remains unknown in most patients. We reported a pediatric case with ITP whose COVID-19 total antibody test was positive. Despite the poor response of high dose intravenous immunoglobulin (IVIG), steroid treatment generated a good result. Our patient had an asymptomatic Severe Acute Respiratory Syndrome Coronavirus 2, SARSCoV-2 infection (COVID-19 infection) and COVID-19 PCR was negative. Since we are in the period of the COVID-19-related pandemic, SARS-CoV-2 should be kept in mind in the etiology of ITP. This case raises awareness of both PCR and antibody screening for COVID-19 in patients with ITP, especially in the pandemic season.\",\"PeriodicalId\":8302,\"journal\":{\"name\":\"Archives of pediatrics\",\"volume\":\"102 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-12-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archives of pediatrics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.29011/2575-825x.100096\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of pediatrics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.29011/2575-825x.100096","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A Pediatric Case Report with Immune Thrombocytopenic Purpura Associated with COVID-19
Immune Thrombocytopenic Purpura (ITP) of childhood is identified as isolated thrombocytopenia. While it can be triggered by a viral infection such as hepatitis B, hepatitis C, cytomegalovirus, Epstein-Barr, influenza, herpes, varicella-zoster, and HIV or other immune causes, the reason for ITP remains unknown in most patients. We reported a pediatric case with ITP whose COVID-19 total antibody test was positive. Despite the poor response of high dose intravenous immunoglobulin (IVIG), steroid treatment generated a good result. Our patient had an asymptomatic Severe Acute Respiratory Syndrome Coronavirus 2, SARSCoV-2 infection (COVID-19 infection) and COVID-19 PCR was negative. Since we are in the period of the COVID-19-related pandemic, SARS-CoV-2 should be kept in mind in the etiology of ITP. This case raises awareness of both PCR and antibody screening for COVID-19 in patients with ITP, especially in the pandemic season.