小儿免疫性血小板减少性紫癜合并COVID-19病例报告

Sultan Aydın, Gizem Gülten Altinkaynak
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引用次数: 2

摘要

儿童免疫性血小板减少性紫癜(ITP)是一种孤立性血小板减少症。虽然ITP可由乙型肝炎、丙型肝炎、巨细胞病毒、爱泼斯坦-巴尔病毒、流感、疱疹、水痘带状疱疹和艾滋病毒等病毒感染或其他免疫原因引发,但大多数患者仍不清楚ITP的病因。我们报告1例ITP患儿,其COVID-19总抗体检测呈阳性。尽管高剂量静脉注射免疫球蛋白(IVIG)反应较差,但类固醇治疗效果良好。患者为无症状严重急性呼吸综合征冠状病毒2型,SARSCoV-2感染(COVID-19感染),COVID-19 PCR阴性。由于我们正处于与covid -19相关的大流行时期,因此在ITP的病因学中应牢记SARS-CoV-2。该病例提高了ITP患者对COVID-19 PCR和抗体筛查的认识,特别是在大流行季节。
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A Pediatric Case Report with Immune Thrombocytopenic Purpura Associated with COVID-19
Immune Thrombocytopenic Purpura (ITP) of childhood is identified as isolated thrombocytopenia. While it can be triggered by a viral infection such as hepatitis B, hepatitis C, cytomegalovirus, Epstein-Barr, influenza, herpes, varicella-zoster, and HIV or other immune causes, the reason for ITP remains unknown in most patients. We reported a pediatric case with ITP whose COVID-19 total antibody test was positive. Despite the poor response of high dose intravenous immunoglobulin (IVIG), steroid treatment generated a good result. Our patient had an asymptomatic Severe Acute Respiratory Syndrome Coronavirus 2, SARSCoV-2 infection (COVID-19 infection) and COVID-19 PCR was negative. Since we are in the period of the COVID-19-related pandemic, SARS-CoV-2 should be kept in mind in the etiology of ITP. This case raises awareness of both PCR and antibody screening for COVID-19 in patients with ITP, especially in the pandemic season.
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