Khadija Hafidh, Saira Abbas, Arhsee Khan, Touseef Kazmi, Zufana Nazir, T. Aldaham
{"title":"阿联酋三级医疗中心糖尿病患者COVID-19感染的临床特征和结局","authors":"Khadija Hafidh, Saira Abbas, Arhsee Khan, Touseef Kazmi, Zufana Nazir, T. Aldaham","doi":"10.1159/000512232","DOIUrl":null,"url":null,"abstract":"Introduction: Uncontrolled glycemia is a well-recognized predictor of severity and deaths in previous respiratory viral outbreaks. We aimed to describe the characteristics and clinical course of patients with diabetes admitted with COVID-19 infection at a tertiary care center in the Emirate of Dubai, UAE, and assess the impact of hyperglycemia on the clinical outcomes. Methods: This study is a single-center, observational, retrospective chart review of 250 cases during the months of March to May 2020. Results: Among the 250 cases studied, 235 (94%) were male. The mean age of the study group was 49.6 ± 10.4 years, with an age range of 21–78 years. Diabetes was previously known in 166 (66.4%) of the patients. The mortality (p = 0.03) and requirement for mechanical ventilation (p = 0.02) were higher for the cases with newly diagnosed diabetes when compared to those with pre-existing diabetes. Conclusion: Uncontrolled hyperglycemia adversely affects patients with COVID-19 infection. Newly diagnosed and previously undiagnosed hyperglycemia poses an added risk for complications. In the context of the COVID-19 pandemic, optimizing glycemia in hospitalized patients is of paramount importance and screening to detect undiagnosed cases of diabetes may be particularly relevant.","PeriodicalId":34679,"journal":{"name":"Dubai Diabetes and Endocrinology Journal","volume":"59 1","pages":"158 - 163"},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"13","resultStr":"{\"title\":\"The Clinical Characteristics and Outcomes of COVID-19 Infections in Patients with Diabetes at a Tertiary Care Center in the UAE\",\"authors\":\"Khadija Hafidh, Saira Abbas, Arhsee Khan, Touseef Kazmi, Zufana Nazir, T. Aldaham\",\"doi\":\"10.1159/000512232\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction: Uncontrolled glycemia is a well-recognized predictor of severity and deaths in previous respiratory viral outbreaks. We aimed to describe the characteristics and clinical course of patients with diabetes admitted with COVID-19 infection at a tertiary care center in the Emirate of Dubai, UAE, and assess the impact of hyperglycemia on the clinical outcomes. Methods: This study is a single-center, observational, retrospective chart review of 250 cases during the months of March to May 2020. Results: Among the 250 cases studied, 235 (94%) were male. The mean age of the study group was 49.6 ± 10.4 years, with an age range of 21–78 years. Diabetes was previously known in 166 (66.4%) of the patients. The mortality (p = 0.03) and requirement for mechanical ventilation (p = 0.02) were higher for the cases with newly diagnosed diabetes when compared to those with pre-existing diabetes. Conclusion: Uncontrolled hyperglycemia adversely affects patients with COVID-19 infection. Newly diagnosed and previously undiagnosed hyperglycemia poses an added risk for complications. In the context of the COVID-19 pandemic, optimizing glycemia in hospitalized patients is of paramount importance and screening to detect undiagnosed cases of diabetes may be particularly relevant.\",\"PeriodicalId\":34679,\"journal\":{\"name\":\"Dubai Diabetes and Endocrinology Journal\",\"volume\":\"59 1\",\"pages\":\"158 - 163\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"13\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Dubai Diabetes and Endocrinology Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1159/000512232\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dubai Diabetes and Endocrinology Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000512232","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The Clinical Characteristics and Outcomes of COVID-19 Infections in Patients with Diabetes at a Tertiary Care Center in the UAE
Introduction: Uncontrolled glycemia is a well-recognized predictor of severity and deaths in previous respiratory viral outbreaks. We aimed to describe the characteristics and clinical course of patients with diabetes admitted with COVID-19 infection at a tertiary care center in the Emirate of Dubai, UAE, and assess the impact of hyperglycemia on the clinical outcomes. Methods: This study is a single-center, observational, retrospective chart review of 250 cases during the months of March to May 2020. Results: Among the 250 cases studied, 235 (94%) were male. The mean age of the study group was 49.6 ± 10.4 years, with an age range of 21–78 years. Diabetes was previously known in 166 (66.4%) of the patients. The mortality (p = 0.03) and requirement for mechanical ventilation (p = 0.02) were higher for the cases with newly diagnosed diabetes when compared to those with pre-existing diabetes. Conclusion: Uncontrolled hyperglycemia adversely affects patients with COVID-19 infection. Newly diagnosed and previously undiagnosed hyperglycemia poses an added risk for complications. In the context of the COVID-19 pandemic, optimizing glycemia in hospitalized patients is of paramount importance and screening to detect undiagnosed cases of diabetes may be particularly relevant.