阿联酋三级医疗中心糖尿病患者COVID-19感染的临床特征和结局

Khadija Hafidh, Saira Abbas, Arhsee Khan, Touseef Kazmi, Zufana Nazir, T. Aldaham
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引用次数: 13

摘要

未控制的血糖是一个公认的预测严重程度和死亡在以前的呼吸道病毒爆发。我们的目的是描述在阿联酋迪拜酋长国的一家三级保健中心入院的合并COVID-19感染的糖尿病患者的特征和临床病程,并评估高血糖对临床结果的影响。方法:本研究采用单中心、观察性、回顾性的图表分析方法,纳入了2020年3月至5月期间的250例病例。结果:250例病例中,男性235例(94%)。研究组平均年龄49.6±10.4岁,年龄范围21 ~ 78岁。166例(66.4%)患者以前已知糖尿病。新诊断糖尿病患者的死亡率(p = 0.03)和机械通气需求(p = 0.02)高于既往糖尿病患者。结论:未控制的高血糖对COVID-19感染患者不利。新诊断和以前未诊断的高血糖会增加并发症的风险。在2019冠状病毒病大流行的背景下,优化住院患者的血糖至关重要,筛查发现未确诊的糖尿病病例可能尤为重要。
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The Clinical Characteristics and Outcomes of COVID-19 Infections in Patients with Diabetes at a Tertiary Care Center in the UAE
Introduction: Uncontrolled glycemia is a well-recognized predictor of severity and deaths in previous respiratory viral outbreaks. We aimed to describe the characteristics and clinical course of patients with diabetes admitted with COVID-19 infection at a tertiary care center in the Emirate of Dubai, UAE, and assess the impact of hyperglycemia on the clinical outcomes. Methods: This study is a single-center, observational, retrospective chart review of 250 cases during the months of March to May 2020. Results: Among the 250 cases studied, 235 (94%) were male. The mean age of the study group was 49.6 ± 10.4 years, with an age range of 21–78 years. Diabetes was previously known in 166 (66.4%) of the patients. The mortality (p = 0.03) and requirement for mechanical ventilation (p = 0.02) were higher for the cases with newly diagnosed diabetes when compared to those with pre-existing diabetes. Conclusion: Uncontrolled hyperglycemia adversely affects patients with COVID-19 infection. Newly diagnosed and previously undiagnosed hyperglycemia poses an added risk for complications. In the context of the COVID-19 pandemic, optimizing glycemia in hospitalized patients is of paramount importance and screening to detect undiagnosed cases of diabetes may be particularly relevant.
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