p0 - 9a型横向场激发声波传感器检测水中蛤蚌毒素

M. Wark, B. Kalanyan, L. Ellis, J. Fick, L. Connell, D. Neivandt, J. Vetelino
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引用次数: 21

摘要

在美国,大约20%的食源性疾病暴发是由食用海产品引起的。具体来说,麻痹性贝类中毒(PSP)是由于食用被一系列神经毒素污染的软体贝类而引起的,其中最有效的是蛤蚌毒素(STX)。目前检测STX的方法是小鼠生物测定法,其中将小鼠暴露于贝类样本并记录小鼠死亡所需的时间。小鼠死亡所需的时间长度用于估计原始样本中STX的水平。由于这项技术是一项耗时且昂贵的实验室程序,因此需要一种快速的原位传感器来检测贝类和海水中的STX水平,以便及时关闭贝类养殖场,以保护公众健康。在这项工作中,一种新型的横向场激发(LFE)声波传感器已经成功地用于化学和生物传感,用于检测水中的STX,证明了它是一种可行的替代小鼠生物测定法检测STX的方法。
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P0-9 A Lateral Field Excited Acoustic Wave Sensor for the Detection of Saxitoxin in Water
In the United States, approximately 20% of all foodborne disease outbreaks result from the consumption of seafood products. Specifically, the disease Paralytic Shellfish Poisoning (PSP) is caused by consuming molluscan shellfish contaminated with a suite of neurotoxins the most potent of which is saxitoxin (STX). The current method for detecting STX is the mouse bioassay in which a mouse is exposed to a shellfish sample and the time required for the mouse to perish is noted. The length of time required for the mouse to die is used to estimate the level of STX in the original sample. Since this technique is a time consuming and costly laboratory-based procedure, a rapid in situ sensor is needed to detect STX levels in shellfish and in sea water so timely closures of shellfish grounds can be made to protect public health. In this work, a novel Lateral Field Excited (LFE) acoustic wave sensor, which has been successfully used for chemical and biological sensing, is employed to detect STX in water, proving itself as a feasible alternative to the mouse bioassay in STX detection.
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